Xenon Pharmaceuticals Down over 28%, on Pace for Largest Percent Decrease Since March 2017

Dow Jones

Yesterday

Xenon Pharmaceuticals Inc. $(XENE)$ is currently at $41.09, down $16.26 or 28.35%

--Would be lowest close since Feb. 5, 2026, when it closed at $40.39

--On pace for largest percent decrease since March 24, 2017, when it fell 52.79%

--Snaps a two-day winning streak

--Down 29.94% this week; worst weekly performance since the week ending March 24, 2017, when it fell 42.59%

--Down 31.77% month-to-date

--Down 8.32% year-to-date

--Down 42.09% from its all-time closing high of $70.96 on July 9, 2026

--Up 11.2% from 52 weeks ago (Sept. 19, 2025), when it closed at $36.95

--Down 42.09% from its 52-week closing high of $70.96 on July 9, 2026

--Up 12.51% from its 52-week closing low of $36.52 on Sept. 25, 2025

--Traded as low as $39.83; lowest intraday level since Jan. 20, 2026, when it hit $39.29

--Down 30.55% at today's intraday low; largest intraday percent decrease since March 24, 2017, when it fell as much as 56.35%

All data as of 10:38:06 AM ET

Source: Dow Jones Market Data, FactSet

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worst weekly performance since the week ending March 24, 2017, when it fell 42.59% \n</p>\n<p>\n       --Down 31.77% month-to-date \n</p>\n<p>\n       --Down 8.32% year-to-date \n</p>\n<p>\n       --Down 42.09% from its all-time closing high of $70.96 on July 9, 2026 \n</p>\n<p>\n       --Up 11.2% from 52 weeks ago (Sept. 19, 2025), when it closed at $36.95 \n</p>\n<p>\n       --Down 42.09% from its 52-week closing high of $70.96 on July 9, 2026 \n</p>\n<p>\n       --Up 12.51% from its 52-week closing low of $36.52 on Sept. 25, 2025 \n</p>\n<p>\n       --Traded as low as $39.83; lowest intraday level since Jan. 20, 2026, when it hit $39.29 \n</p>\n<p>\n       --Down 30.55% at today's intraday low; largest intraday percent decrease since March 24, 2017, when it fell as much as 56.35% \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n     All data as of 10:38:06 AM ET \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n     Source: Dow Jones Market Data, FactSet \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n</font>","source":null,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; 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worst weekly performance since the week ending March 24, 2017, when it fell 42.59% \n</p>\n<p>\n       --Down 31.77% month-to-date \n</p>\n<p>\n       --Down 8.32% year-to-date \n</p>\n<p>\n       --Down 42.09% from its all-time closing high of $70.96 on July 9, 2026 \n</p>\n<p>\n       --Up 11.2% from 52 weeks ago (Sept. 19, 2025), when it closed at $36.95 \n</p>\n<p>\n       --Down 42.09% from its 52-week closing high of $70.96 on July 9, 2026 \n</p>\n<p>\n       --Up 12.51% from its 52-week closing low of $36.52 on Sept. 25, 2025 \n</p>\n<p>\n       --Traded as low as $39.83; lowest intraday level since Jan. 20, 2026, when it hit $39.29 \n</p>\n<p>\n       --Down 30.55% at today's intraday low; largest intraday percent decrease since March 24, 2017, when it fell as much as 56.35% \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n     All data as of 10:38:06 AM ET \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n     Source: Dow Jones Market Data, FactSet \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n</font>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"SBIO","symbol_name":"ALPS Medical Breakthroughs ETF","start_time":0,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","article_id":"2668771921","we_media_id":"106","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2668771921","pubTimestamp":1789742460,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Dow Jones","introduction":"Dow Jones publishes the world’s most trusted business news and financial information in a variety of media.","home_visible":0,"id":"106","head_image":"https://static.tigerbbs.com/150f88aa4d182df19190059f4a365e99"},"summary":"Xenon Pharmaceuticals Inc.  is currently at $41.09, down $16.26 or 28.35%--Would be lowest close since Feb. 5, 2026, when it closed at $40.39--On pace for largest percent decrease since March 24, 2017, when it fell 52.79%--Snaps a two-day winning streak--Down 29.94% this week; worst weekly performance since the week ending March 24, 2017, when it fell 42.59%--Down 31.77% month-to-date--Down 8.32% year-to-date--Down 42.09% from its all-time closing high of $70.96 on July 9, 2026--Up 11.2% from 52 weeks ago , when it closed at $36.95--Down 42.09% from its 52-week closing high of $70.96 on July 9, 2026--Up 12.51% from its 52-week closing low of $36.52 on Sept. 25, 2025--Traded as low as $39.83; lowest intraday level since Jan. 20, 2026, when it hit $39.29--Down 30.55% at today's intraday low; largest intraday percent decrease since March 24, 2017, when it fell as much as 56.35%All data as of 10:38:06 AM ETSource: Dow Jones Market Data, FactSet","collect":0,"end_time":0,"defaultTopTitle":"","property":[],"viewcount":null,"language":"en","relate_stocks":{"SBIO":"ALPS Medical Breakthroughs ETF","BK4139":"生物科技","XENE":"Xenon制药","IBRN":"iShares Neuroscience and Healthcare ETF"},"translate_title":"Xenon Pharmaceuticals 股价下跌超过 28%，有望创下 2017 年 3 月以来最大跌幅","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"IBRN":0.6,"XENE":1.5,"SBIO":0.6},"content_text":"Xenon Pharmaceuticals Inc. $(XENE)$ is currently at $41.09, down $16.26 or 28.35% \n\n\n \n\n\n       --Would be lowest close since Feb. 5, 2026, when it closed at $40.39 \n\n\n       --On pace for largest percent decrease since March 24, 2017, when it fell 52.79% \n\n\n       --Snaps a two-day winning streak \n\n\n       --Down 29.94% this week; worst weekly performance since the week ending March 24, 2017, when it fell 42.59% \n\n\n       --Down 31.77% month-to-date \n\n\n       --Down 8.32% year-to-date \n\n\n       --Down 42.09% from its all-time closing high of $70.96 on July 9, 2026 \n\n\n       --Up 11.2% from 52 weeks ago (Sept. 19, 2025), when it closed at $36.95 \n\n\n       --Down 42.09% from its 52-week closing high of $70.96 on July 9, 2026 \n\n\n       --Up 12.51% from its 52-week closing low of $36.52 on Sept. 25, 2025 \n\n\n       --Traded as low as $39.83; lowest intraday level since Jan. 20, 2026, when it hit $39.29 \n\n\n       --Down 30.55% at today's intraday low; largest intraday percent decrease since March 24, 2017, when it fell as much as 56.35% \n\n\n \n\n\n     All data as of 10:38:06 AM ET \n\n\n \n\n\n     Source: Dow Jones Market Data, FactSet","kind":"highlight","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":true,"editions":null,"column":"","sentiment":"-2","news_tag":"","news_rank":0,"isVideo":false,"video":null,"symbols":[],"gpt_button":0,"need_auth":true,"need_login_tip":false,"code":"91000000","status":"200"}}}