US StockDetailed Quotes

Provided by Tiger Trade Technology Pte. Ltd.

Ionis Pharmaceuticals

46.78

-0.4700-0.99%

Volume:2.46M

Turnover:115.06M

Market Cap:7.77B

PE:-13.44

High:47.59

Open:47.20

Low:46.39

Close:47.25

52wk High:86.74

52wk Low:46.39

Shares:166.18M

Float Shares:161.92M

Volume Ratio:1.41

T/O Rate:1.52%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-3.4800

EPS(LYR):-2.3812

ROE:-105.50%

ROA:-12.42%

PB:17.68

PE(LYR):-19.65

Loading ...

Overview Company News Filings

Movement Alert｜Ionis Pharmaceuticals Falls 9.78% Overnight, Partner Novartis Pelacarsen Phase 3 Cardiovascular Outcomes Trial Fails to Meet Primary Endpoint

Citi sees limited immediate downside for Ionis after pelacarsen failure

Stocks to Watch: Ionis Pharmaceuticals, Novartis, Corvex

Ionis Pharmaceuticals Updates on Novartis Pelacarsen Trial Outcome

Novartis announces Phase 3 pelacarsen study did not meet primary endpoint

Ionis-Novartis Heart Drug Misses Main Goal of Late-Stage Trial

Novartis Says Pelacarsen Heart Disease Drug Missed Primary Endpoint

Ionis Pharmaceuticals: Buy Rating Backed by FDA Approval of Zanvastro and Strengthened Neurology Pipeline Upside

Movement Alert｜Ionis Pharmaceuticals Falls 9.43% in After-Hours Trading, FDA Approval of Alexander Disease Drug Triggers Sell-the-News Reaction

Ionis Pharmaceuticals (IONS) Receives a Rating Update from a Top Analyst

This Biotech Wins a Big FDA Approval. Why Wall Street is Shrugging.

Analysts’ Opinions Are Mixed on These Healthcare Stocks: cbdMD (YCBD) and Ionis Pharmaceuticals (IONS)

Ionis Pharmaceuticals' Zanvastro Approval Sets Path for Independent Neurology Business, Oppenheimer Says

MT Newswires Live

Ionis Pharmaceuticals Exec Says Zanvastro Will be Available at List Price of $285,000 Per Dose

THOMSON REUTERS

U.S. Stocks on the MOVE-Lululemon Athletica, Adobe, Ionis Pharmaceuticals

Ionis Pharmaceuticals (IONS) Receives a Hold from BMO Capital

Ionis Pharmaceuticals Price Target Maintained with a $115.00/Share by HC Wainwright & Co.

Ionis Pharma up After US FDA Approves Rare Brain Disorder Treatment

Ionis Pharmaceuticals Gets FDA Approval for Alexander Disease Treatment

MT Newswires Live

U.S. Research Roundup-Ciena Corp, Docusign, Snowflake

{"basename":"","ssrTDKData":{"titleTemplate":"%s - Tiger Brokers","title":"Easy breezy. No more feesies.","description":"Tiger Trade is a mobile trading app offering real time data, low commission fees and a free demo account. Download now to start investing in ETFs, options and the global share market.","keywords":"Tiger Brokers,U.S. stock trading,Hong Kong stock trading,trading U.S. stocks,stock information,stock prices,U.S. stock quotes,U.S. stock trading,Hong Kong stock trading,IPO trading,buying U.S. stocks,global investment","social":{"ogDescription":"Tiger Trade is a mobile trading app offering real time data, low commission fees and a free demo account. Download now to start investing in ETFs, options and the global share market.","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.0a0bd8dc.png","ogUrl":"https://www.thetigerbrokers.com/stock/IONS/news?page=2"},"companyName":"Tiger Brokers"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"NZL","license":"TBKIWI","edition":"fundamental","symbol":"IONS","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"IONS\",,,,,undefined,":{"symbol":"IONS","market":"US","secType":"STK","nameCN":"Ionis Pharmaceuticals","latestPrice":46.78,"timestamp":1789575094078,"preClose":47.25,"halted":0,"volume":2462655,"delay":0,"changeRate":-0.009947089947089923,"floatShares":161921007,"shares":166184322,"eps":-3.48,"marketStatus":"Trading","change":-0.47,"latestTime":"09-16 12:11:35 EDT","open":47.2,"high":47.59,"low":46.39,"amount":115055315.47965,"amplitude":0.025397,"askPrice":46.85,"askSize":70,"bidPrice":46.78,"bidSize":476,"shortable":3,"etf":0,"ttmEps":-3.48,"tradingStatus":2,"nextMarketStatus":{"tag":"Post-Mkt","tradingStatus":3,"beginTime":1789588800000},"marketStatusCode":2,"adr":0,"adrRate":0,"exchange":"NASDAQ","adjPreClose":47.25,"preHourTrading":{"tag":"盘前","latestPrice":47.21,"preClose":47.25,"latestTime":"09:29 EDT","volume":7343,"amount":347911.54560400004,"timestamp":1789565399999,"change":-0.04,"changeRate":-0.000847,"amplitude":0.01037},"postHourTrading":{"tag":"盘后","latestPrice":47.98,"preClose":47.25,"latestTime":"19:57 EDT","volume":118240,"amount":5600833.0441,"timestamp":1789516638620,"change":0.73,"changeRate":0.01545,"amplitude":0.01545},"volumeRatio":1.407683,"impliedVol":0.504,"impliedVolPercentile":0.7729},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"IONS\",,,,,undefined,":{"symbol":"IONS","floatShares":161921007,"roa":"-12.42%","roe":"-105.50%","lyrEps":-2.38125,"volumeRatio":1.407683,"shares":166184322,"dividePrice":0,"high":47.59,"amplitude":0.025397,"preClose":47.25,"low":46.39,"week52Low":46.39,"pbRate":"17.68","psRate":"8.89","week52High":86.74,"institutionHeld":0.92,"latestPrice":46.78,"committee":0.74359,"eps":-3.48,"divideRate":0,"volume":2462655,"delay":0,"ttmEps":-3.48,"open":47.2,"prevYearClose":79.11,"prevWeekClose":54.21,"prevMonthClose":60.36,"prevQuarterClose":79.29,"fiveDayClose":56.02,"twentyDayClose":59.62,"sixtyDayClose":75.89},"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/IONS\",params:#limit:5,,,undefined,":[{"market":"US","date":"2026-07-29","symbol":"IONS","fiscalQuarterEnding":"2026/06","expectedEps":-1.09,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1785297600000,"reportTimeType":"pre","actualEps":-0.7},{"market":"US","date":"2026-04-29","symbol":"IONS","fiscalQuarterEnding":"2026/03","expectedEps":-0.89,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1777435200000,"reportTimeType":"pre","actualEps":-0.56},{"market":"US","date":"2026-02-25","symbol":"IONS","fiscalQuarterEnding":"2025/12","expectedEps":-1.31,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1771995600000,"reportTimeType":"pre","actualEps":-1.41},{"market":"US","date":"2025-10-29","symbol":"IONS","fiscalQuarterEnding":"2025/09","expectedEps":-1.23,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1761710400000,"reportTimeType":"pre","actualEps":-0.8},{"market":"US","date":"2025-07-30","symbol":"IONS","fiscalQuarterEnding":"2025/06","expectedEps":-0.11,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1753848000000,"reportTimeType":"pre","actualEps":0.7}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"IONS\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"IONS\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0.2308,"buy":0.5385,"hold":0.2308,"sell":0,"strongSell":0,"meanLabel":"BUY","meanPercent":0.5385,"analysts":26,"updateTime":1787112000000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/IONS\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"IONS","date":"2026-09-15","current":-13.577586,"percent":0.719284,"low":-1664.931905,"twenty":-46.83029,"median":-17.982683,"eighty":-11.712128,"high":882.260453,"avg":-65.18325,"sd":366.233599,"marketCap":8548521523},"quantilePoints":[{"date":"2021-09-17","current":-9.553748,"twenty":-43.823694,"median":22.105712,"eighty":90.484478,"marketCap":5252105842},{"date":"2021-09-24","current":-9.294428,"twenty":-43.823694,"median":21.894477,"eighty":89.822908,"marketCap":5109546667},{"date":"2021-10-01","current":-8.61917,"twenty":-43.823694,"median":21.739571,"eighty":88.160122,"marketCap":4738328221},{"date":"2021-10-08","current":-8.752681,"twenty":-43.823694,"median":21.475528,"eighty":87.371554,"marketCap":4811725024},{"date":"2021-10-15","current":-9.012001,"twenty":-43.823694,"median":21.145012,"eighty":86.264015,"marketCap":4954284199},{"date":"2021-10-22","current":-7.815535,"twenty":-43.823694,"median":21.004285,"eighty":84.663252,"marketCap":4296535927},{"date":"2021-10-29","current":-8.182691,"twenty":-43.823694,"median":20.82218,"eighty":83.19244,"marketCap":4498377135},{"date":"2021-11-05","current":-7.827936,"twenty":-43.823694,"median":20.669316,"eighty":82.070133,"marketCap":4757365405},{"date":"2021-11-12","current":-7.595584,"twenty":-43.823694,"median":20.616507,"eighty":76.079084,"marketCap":4616155390},{"date":"2021-11-19","current":-7.432938,"twenty":-43.823694,"median":20.366546,"eighty":75.49578,"marketCap":4517308379},{"date":"2021-11-26","current":-6.749823,"twenty":-43.823694,"median":20.294106,"eighty":74.547727,"marketCap":4102150935},{"date":"2021-12-03","current":-6.131767,"twenty":-43.823694,"median":20.173015,"eighty":74.030875,"marketCap":3726532295},{"date":"2021-12-10","current":-6.847411,"twenty":-43.823694,"median":20.114106,"eighty":72.607318,"marketCap":4161459142},{"date":"2021-12-17","current":-7.542143,"twenty":-43.823694,"median":20.025743,"eighty":70.436541,"marketCap":4583677086},{"date":"2021-12-23","current":-7.600231,"twenty":-43.823694,"median":19.891562,"eighty":60.214071,"marketCap":4618979590},{"date":"2021-12-31","current":-7.070469,"twenty":-43.823694,"median":19.796653,"eighty":53.012098,"marketCap":4297020756},{"date":"2022-01-07","current":-7.058851,"twenty":-43.611673,"median":19.749198,"eighty":51.923862,"marketCap":4289960255},{"date":"2022-01-14","current":-7.686201,"twenty":-43.611673,"median":19.64938,"eighty":51.147099,"marketCap":4671227296},{"date":"2022-01-21","current":-6.942675,"twenty":-43.611673,"median":19.61175,"eighty":50.934296,"marketCap":4219355248},{"date":"2022-01-28","current":-7.360909,"twenty":-43.611673,"median":19.468798,"eighty":50.847883,"marketCap":4473533275},{"date":"2022-02-04","current":-7.319085,"twenty":-43.611673,"median":19.28882,"eighty":50.5876,"marketCap":4448115472},{"date":"2022-02-11","current":-7.639731,"twenty":-43.611673,"median":19.164904,"eighty":50.143461,"marketCap":4642985293},{"date":"2022-02-18","current":-7.497996,"twenty":-43.611673,"median":18.965356,"eighty":49.908881,"marketCap":4556847184},{"date":"2022-02-25","current":-157.459445,"twenty":-44.533501,"median":18.77393,"eighty":49.713145,"marketCap":4502867744},{"date":"2022-03-04","current":-160.035874,"twenty":-45.829592,"median":18.155386,"eighty":49.32903,"marketCap":4576545882},{"date":"2022-03-11","current":-159.49086,"twenty":-46.633425,"median":-6.144547,"eighty":48.69515,"marketCap":4560960122},{"date":"2022-03-18","current":-174.652153,"twenty":-47.12015,"median":-6.881102,"eighty":48.427938,"marketCap":4994527626},{"date":"2022-03-25","current":-181.687786,"twenty":-47.927671,"median":-7.000763,"eighty":48.265452,"marketCap":5195725619},{"date":"2022-04-01","current":-192.736702,"twenty":-48.230031,"median":-7.040263,"eighty":47.833218,"marketCap":5511691480},{"date":"2022-04-08","current":-198.781401,"twenty":-48.689101,"median":-7.082087,"eighty":47.228668,"marketCap":5684551727},{"date":"2022-04-14","current":-202.992871,"twenty":-49.716018,"median":-7.119262,"eighty":46.918857,"marketCap":5804987145},{"date":"2022-04-22","current":-206.852389,"twenty":-50.435043,"median":-7.237762,"eighty":46.570634,"marketCap":5915357781},{"date":"2022-04-29","current":-182.216483,"twenty":-51.591015,"median":-7.300497,"eighty":46.245658,"marketCap":5210844764},{"date":"2022-05-06","current":-1322.183946,"twenty":-128.214398,"median":-7.341159,"eighty":45.925265,"marketCap":5147262100},{"date":"2022-05-13","current":-1314.170709,"twenty":-130.326929,"median":-7.37485,"eighty":45.90793,"marketCap":5116066572},{"date":"2022-05-20","current":-1438.375868,"twenty":-130.86667,"median":-7.37485,"eighty":45.90793,"marketCap":5599597254},{"date":"2022-05-27","current":-1370.6276,"twenty":-132.625178,"median":-7.37485,"eighty":45.90793,"marketCap":5335853246},{"date":"2022-06-03","current":-1316.720376,"twenty":-134.128325,"median":-7.37485,"eighty":45.90793,"marketCap":5125992422},{"date":"2022-06-10","current":-1266.091293,"twenty":-137.45382,"median":-7.37485,"eighty":45.90793,"marketCap":4928893405},{"date":"2022-06-17","current":-1284.303193,"twenty":-139.005646,"median":-7.37485,"eighty":45.90793,"marketCap":4999792332},{"date":"2022-06-24","current":-1429.634156,"twenty":-139.862338,"median":-7.360909,"eighty":45.909339,"marketCap":5565565769},{"date":"2022-07-01","current":-1386.289834,"twenty":-141.353878,"median":-7.360909,"eighty":45.909339,"marketCap":5396826323},{"date":"2022-07-08","current":-1353.144176,"twenty":-142.456573,"median":-7.360909,"eighty":45.909339,"marketCap":5267790276},{"date":"2022-07-15","current":-1431.819584,"twenty":-143.808127,"median":-7.360909,"eighty":45.909339,"marketCap":5574073640},{"date":"2022-07-22","current":-1387.746786,"twenty":-144.656772,"median":-7.360909,"eighty":45.909339,"marketCap":5402498237},{"date":"2022-07-29","current":-1368.077934,"twenty":-146.022974,"median":-7.360909,"eighty":45.909339,"marketCap":5325927396},{"date":"2022-08-05","current":-1664.567667,"twenty":-147.819198,"median":-7.360909,"eighty":45.909339,"marketCap":6480161927},{"date":"2022-08-12","current":-222.342663,"twenty":-148.698169,"median":-7.360909,"eighty":45.909339,"marketCap":6259613005},{"date":"2022-08-19","current":-221.838485,"twenty":-149.407406,"median":-7.360909,"eighty":45.909339,"marketCap":6245418872},{"date":"2022-08-26","current":-213.519542,"twenty":-149.883165,"median":-7.360909,"eighty":45.909339,"marketCap":6011215664},{"date":"2022-09-02","current":-218.006729,"twenty":-150.165357,"median":-7.360909,"eighty":45.909339,"marketCap":6137543455},{"date":"2022-09-09","current":-236.157151,"twenty":-151.092649,"median":-7.360909,"eighty":45.909339,"marketCap":6648532271},{"date":"2022-09-16","current":-233.585841,"twenty":-153.529951,"median":-7.360909,"eighty":45.909339,"marketCap":6576142189},{"date":"2022-09-23","current":-217.956312,"twenty":-156.46647,"median":-7.360909,"eighty":45.909339,"marketCap":6136124041},{"date":"2022-09-30","current":-222.998095,"twenty":-157.969129,"median":-7.360909,"eighty":45.909339,"marketCap":6278065379},{"date":"2022-10-07","current":-231.569128,"twenty":-159.577078,"median":-7.360909,"eighty":45.909339,"marketCap":6519365654},{"date":"2022-10-14","current":-233.737095,"twenty":-160.082841,"median":-7.360909,"eighty":45.909339,"marketCap":6580400429},{"date":"2022-10-21","current":-226.62818,"twenty":-160.43291,"median":-7.360909,"eighty":45.909339,"marketCap":6380263143},{"date":"2022-10-28","current":-224.913973,"twenty":-161.94987,"median":-7.360909,"eighty":45.909339,"marketCap":6332003088},{"date":"2022-11-04","current":-209.486115,"twenty":-162.370971,"median":-7.360909,"eighty":45.909339,"marketCap":5897662593},{"date":"2022-11-11","current":839.185498,"twenty":-162.756411,"median":-7.319085,"eighty":46.031035,"marketCap":6143677032},{"date":"2022-11-18","current":836.080997,"twenty":-162.756411,"median":-7.284232,"eighty":46.34415,"marketCap":6120948978},{"date":"2022-11-25","current":806.394204,"twenty":-162.756411,"median":-7.219174,"eighty":46.64061,"marketCap":5903611964},{"date":"2022-12-02","current":782.334319,"twenty":-162.756411,"median":-7.102998,"eighty":47.141347,"marketCap":5727469547},{"date":"2022-12-09","current":727.617484,"twenty":-162.756411,"median":-7.058851,"eighty":47.387939,"marketCap":5326887600},{"date":"2022-12-16","current":750.125118,"twenty":-162.756411,"median":-7.014704,"eighty":48.047842,"marketCap":5491665989},{"date":"2022-12-23","current":740.423552,"twenty":-162.756411,"median":-6.972881,"eighty":48.293594,"marketCap":5420640821},{"date":"2022-12-30","current":732.85633,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5365241190},{"date":"2023-01-06","current":786.214945,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5755879614},{"date":"2023-01-13","current":773.214846,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5660705889},{"date":"2023-01-20","current":790.871697,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5789971695},{"date":"2023-01-27","current":776.513379,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5684854446},{"date":"2023-02-03","current":793.976198,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5812699749},{"date":"2023-02-10","current":756.722183,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5539963104},{"date":"2023-02-17","current":748.96093,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5483142969},{"date":"2023-02-24","current":-18.915876,"twenty":-162.756411,"median":-6.942675,"eighty":48.318169,"marketCap":5102028010},{"date":"2023-03-03","current":-19.398181,"twenty":-162.756411,"median":-7.010057,"eighty":48.167441,"marketCap":5232116143},{"date":"2023-03-10","current":-17.998968,"twenty":-162.756411,"median":-7.047233,"eighty":47.522459,"marketCap":4854717602},{"date":"2023-03-17","current":-18.645574,"twenty":-162.756411,"median":-7.096027,"eighty":47.151665,"marketCap":5029121473},{"date":"2023-03-24","current":-17.993668,"twenty":-162.756411,"median":-7.188968,"eighty":46.719576,"marketCap":4853288062},{"date":"2023-03-31","current":-18.942377,"twenty":-162.739653,"median":-7.283071,"eighty":46.447558,"marketCap":5109175709},{"date":"2023-04-06","current":-19.392881,"twenty":-162.739653,"median":-7.309791,"eighty":46.139197,"marketCap":5230686603},{"date":"2023-04-14","current":-19.906986,"twenty":-162.756411,"median":-7.388791,"eighty":45.881909,"marketCap":5369351977},{"date":"2023-04-21","current":-19.158378,"twenty":-162.756411,"median":-7.484055,"eighty":45.586713,"marketCap":5167435947},{"date":"2023-04-28","current":-18.691747,"twenty":-162.756411,"median":-7.542143,"eighty":45.238708,"marketCap":5041575343},{"date":"2023-05-05","current":-15.654507,"twenty":-162.722895,"median":-7.581643,"eighty":45.096531,"marketCap":5148454369},{"date":"2023-05-12","current":-15.484823,"twenty":-162.005118,"median":-7.581643,"eighty":45.096531,"marketCap":5092648444},{"date":"2023-05-19","current":-15.937315,"twenty":-160.611822,"median":-7.581643,"eighty":45.096531,"marketCap":5241464245},{"date":"2023-05-26","current":-17.042442,"twenty":-160.205418,"median":-7.581643,"eighty":45.096531,"marketCap":5604918222},{"date":"2023-06-02","current":-18.682728,"twenty":-159.773437,"median":-7.581643,"eighty":45.096531,"marketCap":6144375503},{"date":"2023-06-09","current":-18.121463,"twenty":-159.192484,"median":-7.581643,"eighty":45.096531,"marketCap":5959786673},{"date":"2023-06-16","current":-18.138866,"twenty":-156.985977,"median":-7.581643,"eighty":45.096531,"marketCap":5965510357},{"date":"2023-06-23","current":-17.925673,"twenty":-155.435521,"median":-7.578157,"eighty":45.109315,"marketCap":5895395220},{"date":"2023-06-30","current":-17.886515,"twenty":-151.740635,"median":-7.574672,"eighty":45.122099,"marketCap":5882516929},{"date":"2023-07-07","current":-18.169323,"twenty":-150.657265,"median":-7.574672,"eighty":45.122099,"marketCap":5975526805},{"date":"2023-07-14","current":-18.560903,"twenty":-150.083568,"median":-7.574672,"eighty":45.122099,"marketCap":6104309711},{"date":"2023-07-21","current":-17.821251,"twenty":-149.641501,"median":-7.574672,"eighty":45.122099,"marketCap":5861053112},{"date":"2023-07-28","current":-16.750932,"twenty":-149.090615,"median":-7.574672,"eighty":45.122099,"marketCap":5509046504},{"date":"2023-08-04","current":-17.151214,"twenty":-148.303568,"median":-7.574672,"eighty":45.122099,"marketCap":5640691252},{"date":"2023-08-11","current":-18.467972,"twenty":-148.00823,"median":-7.574672,"eighty":45.122099,"marketCap":5707249602},{"date":"2023-08-18","current":-18.147959,"twenty":-147.735407,"median":-7.574672,"eighty":45.122099,"marketCap":5608354519},{"date":"2023-08-25","current":-18.463334,"twenty":-145.579013,"median":-7.574672,"eighty":45.122099,"marketCap":5705816340},{"date":"2023-09-01","current":-18.676675,"twenty":-145.219114,"median":-7.574672,"eighty":45.122099,"marketCap":5771746396},{"date":"2023-09-08","current":-18.727692,"twenty":-145.219114,"median":-7.574672,"eighty":45.122099,"marketCap":5787512279},{"date":"2023-09-15","current":-20.239635,"twenty":-145.219114,"median":-7.574672,"eighty":45.122099,"marketCap":6254755717},{"date":"2023-09-22","current":-19.701643,"twenty":-144.797122,"median":-7.574672,"eighty":45.122099,"marketCap":6088497315},{"date":"2023-09-29","current":-21.454756,"twenty":-143.400598,"median":-7.574672,"eighty":45.122099,"marketCap":6630270382},{"date":"2023-10-06","current":-21.728389,"twenty":-143.032342,"median":-7.574672,"eighty":45.122099,"marketCap":6714832844},{"date":"2023-10-13","current":-21.38055,"twenty":-143.032342,"median":-7.574672,"eighty":45.122099,"marketCap":6607338188},{"date":"2023-10-20","current":-21.593891,"twenty":-143.032342,"median":-7.574672,"eighty":45.122099,"marketCap":6673268244},{"date":"2023-10-27","current":-21.16257,"twenty":-143.300049,"median":-7.55957,"eighty":45.146419,"marketCap":6539974871},{"date":"2023-11-03","current":-15.297336,"twenty":-140.032184,"median":-7.55957,"eighty":45.146419,"marketCap":6267655075},{"date":"2023-11-10","current":-16.577399,"twenty":-22.395314,"median":-7.55957,"eighty":45.146419,"marketCap":6787665949},{"date":"2023-11-17","current":-17.008391,"twenty":-21.672735,"median":-7.55957,"eighty":45.146419,"marketCap":6964136656},{"date":"2023-11-24","current":-17.460406,"twenty":-21.484438,"median":-7.55957,"eighty":45.146419,"marketCap":7149215689},{"date":"2023-12-01","current":-17.334262,"twenty":-21.2275,"median":-7.55957,"eighty":45.146419,"marketCap":7097565726},{"date":"2023-12-08","current":-17.334262,"twenty":-20.411236,"median":-7.572349,"eighty":45.140651,"marketCap":7097565726},{"date":"2023-12-15","current":-17.456902,"twenty":-20.127399,"median":-7.572349,"eighty":45.140651,"marketCap":7147780968},{"date":"2023-12-22","current":-17.208119,"twenty":-19.907658,"median":-7.572349,"eighty":45.140651,"marketCap":7045915764},{"date":"2023-12-29","current":-17.695174,"twenty":-19.76602,"median":-7.55957,"eighty":45.146419,"marketCap":7245342009},{"date":"2024-01-05","current":-18.038565,"twenty":-19.665059,"median":-7.54679,"eighty":45.152187,"marketCap":7385944686},{"date":"2024-01-12","current":-18.763892,"twenty":-19.458602,"median":-7.54679,"eighty":45.152187,"marketCap":7682931972},{"date":"2024-01-19","current":-17.747734,"twenty":-19.2678,"median":-7.544467,"eighty":45.157955,"marketCap":7266862827},{"date":"2024-01-26","current":-18.073605,"twenty":-19.134896,"median":-7.54679,"eighty":45.152187,"marketCap":7400291898},{"date":"2024-02-02","current":-17.859862,"twenty":-19.007278,"median":-7.54679,"eighty":45.152187,"marketCap":7312773905},{"date":"2024-02-09","current":-17.512966,"twenty":-18.941814,"median":-7.54679,"eighty":45.152187,"marketCap":7170736507},{"date":"2024-02-16","current":-15.866089,"twenty":-18.881956,"median":-7.54679,"eighty":45.152187,"marketCap":6496417548},{"date":"2024-02-23","current":-17.500434,"twenty":-18.811317,"median":-7.54679,"eighty":45.152187,"marketCap":6410164032},{"date":"2024-03-01","current":-17.989873,"twenty":-18.791838,"median":-7.578157,"eighty":45.146419,"marketCap":6589438742},{"date":"2024-03-08","current":-17.774998,"twenty":-18.791838,"median":-7.603716,"eighty":45.146419,"marketCap":6510732771},{"date":"2024-03-15","current":-16.784182,"twenty":-18.791838,"median":-7.673842,"eighty":45.146419,"marketCap":6147810797},{"date":"2024-03-22","current":-17.010995,"twenty":-18.791838,"median":-7.777023,"eighty":45.146419,"marketCap":6230889321},{"date":"2024-03-28","current":-17.771018,"twenty":-18.791838,"median":-7.81825,"eighty":45.146419,"marketCap":6509275254},{"date":"2024-04-05","current":-17.042828,"twenty":-18.796083,"median":-7.904612,"eighty":45.152187,"marketCap":6242549465},{"date":"2024-04-12","current":-16.911516,"twenty":-18.796083,"median":-8.182691,"eighty":45.152187,"marketCap":6194451372},{"date":"2024-04-19","current":-16.239034,"twenty":-18.796083,"median":-8.560117,"eighty":45.152187,"marketCap":5948130835},{"date":"2024-04-26","current":-16.659633,"twenty":-18.791838,"median":-8.646128,"eighty":45.146419,"marketCap":6102190447},{"date":"2024-05-03","current":-17.157352,"twenty":-18.791838,"median":-8.845112,"eighty":45.146419,"marketCap":6284497762},{"date":"2024-05-10","current":-14.961134,"twenty":-18.791838,"median":-9.293144,"eighty":45.146419,"marketCap":5756535778},{"date":"2024-05-17","current":-14.25989,"twenty":-18.791838,"median":-9.334225,"eighty":45.146419,"marketCap":5486720952},{"date":"2024-05-24","current":-14.40393,"twenty":-18.791838,"median":-9.552464,"eighty":45.146419,"marketCap":5542142376},{"date":"2024-05-31","current":-13.854306,"twenty":-18.791838,"median":-9.739892,"eighty":45.146419,"marketCap":5330665890},{"date":"2024-06-07","current":-15.112755,"twenty":-18.791838,"median":-9.90935,"eighty":45.146419,"marketCap":5814874119},{"date":"2024-06-14","current":-15.586568,"twenty":-18.796083,"median":-9.987659,"eighty":45.152187,"marketCap":5997181434},{"date":"2024-06-21","current":-15.469062,"twenty":-18.800329,"median":-10.068299,"eighty":45.157955,"marketCap":5951969220},{"date":"2024-06-28","current":-17.902568,"twenty":-18.809069,"median":-10.099656,"eighty":45.171414,"marketCap":6888299589},{"date":"2024-07-05","current":-17.284716,"twenty":-18.809069,"median":-10.146845,"eighty":45.171414,"marketCap":6650570851},{"date":"2024-07-12","current":-17.932892,"twenty":-18.809069,"median":-10.187925,"eighty":45.171414,"marketCap":6899967258},{"date":"2024-07-15","current":-18.194437,"twenty":-18.809069,"median":-10.208466,"eighty":45.171414,"marketCap":7000600896},{"date":"2024-08-02","current":-20.490271,"twenty":-18.868176,"median":-10.389456,"eighty":45.307924,"marketCap":7484809124},{"date":"2024-08-09","current":-18.992918,"twenty":-18.884076,"median":-10.451704,"eighty":45.307924,"marketCap":6946488933},{"date":"2024-08-16","current":-18.655115,"twenty":-18.884076,"median":-10.488762,"eighty":45.307924,"marketCap":6822940561},{"date":"2024-08-23","current":-19.004911,"twenty":-18.92096,"median":-10.554325,"eighty":45.307924,"marketCap":6950875266},{"date":"2024-08-30","current":-19.948361,"twenty":-18.942377,"median":-10.636992,"eighty":45.307924,"marketCap":7295933440},{"date":"2024-09-06","current":-19.248769,"twenty":-18.979477,"median":-10.675476,"eighty":45.307924,"marketCap":7040064031},{"date":"2024-09-13","current":-17.667381,"twenty":-18.992918,"median":-10.762419,"eighty":45.307924,"marketCap":6461685590},{"date":"2024-09-20","current":-18.408188,"twenty":-18.992918,"median":-10.826557,"eighty":45.307924,"marketCap":6732629014},{"date":"2024-09-27","current":-17.701837,"twenty":-18.992918,"median":-11.068858,"eighty":45.307924,"marketCap":6474287610},{"date":"2024-10-04","current":-16.284829,"twenty":-18.992918,"median":-11.242743,"eighty":45.307924,"marketCap":5956029551},{"date":"2024-10-11","current":-16.345127,"twenty":-18.992918,"median":-12.040191,"eighty":45.307924,"marketCap":5978083085},{"date":"2024-10-18","current":-16.577706,"twenty":-18.992918,"median":-13.03948,"eighty":45.307924,"marketCap":6063146718},{"date":"2024-10-25","current":-16.698302,"twenty":-18.992918,"median":-13.446915,"eighty":45.307924,"marketCap":6107253787},{"date":"2024-10-31","current":-16.909346,"twenty":-18.992918,"median":-13.562755,"eighty":45.307924,"marketCap":6184441157},{"date":"2024-11-08","current":-16.902216,"twenty":-18.995317,"median":-13.748329,"eighty":45.31946,"marketCap":6072729658},{"date":"2024-11-15","current":-16.383322,"twenty":-18.995317,"median":-13.840323,"eighty":45.31946,"marketCap":5878515995},{"date":"2024-11-22","current":-14.935534,"twenty":-18.995317,"median":-14.176174,"eighty":45.31946,"marketCap":5359033920},{"date":"2024-11-29","current":-15.723236,"twenty":-18.995317,"median":-14.25989,"eighty":45.31946,"marketCap":5641670064},{"date":"2024-12-06","current":-16.172094,"twenty":-18.995317,"median":-14.506273,"eighty":45.31946,"marketCap":5802725297},{"date":"2024-12-13","current":-16.286509,"twenty":-18.995317,"median":-14.813304,"eighty":45.31946,"marketCap":5843778591},{"date":"2024-12-20","current":-15.661628,"twenty":-18.995317,"median":-14.935534,"eighty":45.31946,"marketCap":5619564444},{"date":"2024-12-27","current":-15.98727,"twenty":-18.995317,"median":-15.08243,"eighty":45.31946,"marketCap":5736408436},{"date":"2025-01-03","current":-15.265577,"twenty":-18.995317,"median":-15.112755,"eighty":45.31946,"marketCap":5477456886},{"date":"2025-01-10","current":-15.005943,"twenty":-18.997715,"median":-15.244128,"eighty":45.330996,"marketCap":5384297486},{"date":"2025-01-17","current":-14.205039,"twenty":-18.997715,"median":-15.281457,"eighty":45.330996,"marketCap":5096924424},{"date":"2025-01-24","current":-15.164364,"twenty":-18.997715,"median":-15.281457,"eighty":45.330996,"marketCap":5441140510},{"date":"2025-01-31","current":-14.662699,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":5261137602},{"date":"2025-02-07","current":-14.359059,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":5152188474},{"date":"2025-02-14","current":-13.35573,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":4792182660},{"date":"2025-02-21","current":-11.446164,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":5196558396},{"date":"2025-02-28","current":-10.979464,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":4983545602},{"date":"2025-03-07","current":-12.044139,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5466798509},{"date":"2025-03-14","current":-11.522308,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5229940998},{"date":"2025-03-21","current":-11.46277,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5202916987},{"date":"2025-03-28","current":-11.109046,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5042362567},{"date":"2025-04-04","current":-9.988335,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":4533675297},{"date":"2025-04-11","current":-9.354433,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":4245949060},{"date":"2025-04-17","current":-9.928797,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":4506651286},{"date":"2025-04-25","current":-10.356068,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":4700588308},{"date":"2025-05-02","current":-11.018739,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5046935029},{"date":"2025-05-09","current":-11.380123,"twenty":-19.000114,"median":-15.297336,"eighty":45.26178,"marketCap":5212460492},{"date":"2025-05-16","current":-11.463519,"twenty":-19.000114,"median":-15.297336,"eighty":45.175259,"marketCap":5250658676},{"date":"2025-05-23","current":-11.55734,"twenty":-19.000114,"median":-15.297336,"eighty":45.175259,"marketCap":5293631632},{"date":"2025-05-30","current":-11.626837,"twenty":-19.000114,"median":-15.297336,"eighty":45.007986,"marketCap":5325463452},{"date":"2025-06-06","current":-12.24536,"twenty":-19.000114,"median":-15.297336,"eighty":44.117786,"marketCap":5608766648},{"date":"2025-06-13","current":-12.377404,"twenty":-19.000114,"median":-15.297336,"eighty":-6.098308,"marketCap":5669247106},{"date":"2025-06-20","current":-12.860408,"twenty":-19.002512,"median":-15.301886,"eighty":-6.769341,"marketCap":5890478253},{"date":"2025-06-27","current":-13.82294,"twenty":-19.002512,"median":-15.301886,"eighty":-6.989146,"marketCap":6331348958},{"date":"2025-07-03","current":-14.941841,"twenty":-19.002512,"median":-15.301886,"eighty":-7.017492,"marketCap":6843841257},{"date":"2025-07-11","current":-14.7264,"twenty":-19.002512,"median":-15.301886,"eighty":-7.061175,"marketCap":6745162615},{"date":"2025-07-18","current":-14.653429,"twenty":-19.002512,"median":-15.301886,"eighty":-7.105786,"marketCap":6711739204},{"date":"2025-07-25","current":-14.646479,"twenty":-19.002512,"median":-15.301886,"eighty":-7.221033,"marketCap":6708556022},{"date":"2025-08-01","current":-25.541485,"twenty":-19.026904,"median":-15.342587,"eighty":-7.288415,"marketCap":6850635022},{"date":"2025-08-08","current":-24.394555,"twenty":-19.059439,"median":-15.406519,"eighty":-7.31955,"marketCap":6543009950},{"date":"2025-08-15","current":-25.464231,"twenty":-19.208439,"median":-15.476942,"eighty":-7.439444,"marketCap":6829914162},{"date":"2025-08-22","current":-25.693023,"twenty":-19.327123,"median":-15.573133,"eighty":-7.500784,"marketCap":6891279785},{"date":"2025-08-29","current":-25.32755,"twenty":-19.462842,"median":-15.656683,"eighty":-7.572814,"marketCap":6793254179},{"date":"2025-09-05","current":-35.269594,"twenty":-19.610183,"median":-15.723236,"eighty":-7.595584,"marketCap":9459869441},{"date":"2025-09-12","current":-38.056694,"twenty":-19.731561,"median":-15.763036,"eighty":-7.642541,"marketCap":10207414305},{"date":"2025-09-19","current":-36.689886,"twenty":-19.905803,"median":-15.876073,"eighty":-7.741966,"marketCap":9840814478},{"date":"2025-09-26","current":-37.420831,"twenty":-20.021346,"median":-16.03996,"eighty":-7.801291,"marketCap":10036865690},{"date":"2025-10-03","current":-40.647687,"twenty":-20.250766,"median":-16.203648,"eighty":-7.855354,"marketCap":10902360063},{"date":"2025-10-10","current":-41.758962,"twenty":-20.936243,"median":-16.267488,"eighty":-8.057965,"marketCap":11200421661},{"date":"2025-10-17","current":-43.422902,"twenty":-21.44548,"median":-16.302057,"eighty":-8.466659,"marketCap":11646717103},{"date":"2025-10-24","current":-42.489907,"twenty":-21.627284,"median":-16.365719,"eighty":-8.619683,"marketCap":11396472873},{"date":"2025-10-31","current":-46.865674,"twenty":-22.311833,"median":-16.491552,"eighty":-8.824572,"marketCap":12013640728},{"date":"2025-11-07","current":-46.821444,"twenty":-24.565703,"median":-16.551864,"eighty":-9.220997,"marketCap":12002302521},{"date":"2025-11-14","current":-44.129685,"twenty":-25.310911,"median":-16.577552,"eighty":-9.310347,"marketCap":11312291607},{"date":"2025-11-21","current":-46.202213,"twenty":-25.459477,"median":-16.623152,"eighty":-9.406991,"marketCap":11843567616},{"date":"2025-11-28","current":-52.274467,"twenty":-25.606854,"median":-16.659586,"eighty":-9.54788,"marketCap":13400141532},{"date":"2025-12-05","current":-51.693149,"twenty":-25.977676,"median":-16.714478,"eighty":-9.709339,"marketCap":13251125091},{"date":"2025-12-12","current":-50.00606,"twenty":-36.254884,"median":-16.738094,"eighty":-9.817591,"marketCap":12818653462},{"date":"2025-12-19","current":-49.051939,"twenty":-36.458718,"median":-16.773398,"eighty":-9.930898,"marketCap":12574072128},{"date":"2025-12-26","current":-50.960181,"twenty":-37.51116,"median":-16.804783,"eighty":-9.964551,"marketCap":13063234795},{"date":"2026-01-02","current":-49.987104,"twenty":-38.080464,"median":-16.872737,"eighty":-9.994875,"marketCap":12813794230},{"date":"2026-01-09","current":-51.522544,"twenty":-40.33867,"median":-16.913584,"eighty":-10.055281,"marketCap":13207392005},{"date":"2026-01-16","current":-48.786554,"twenty":-41.579494,"median":-16.936559,"eighty":-10.101905,"marketCap":12506042883},{"date":"2026-01-23","current":-51.680511,"twenty":-42.352038,"median":-16.969214,"eighty":-10.147872,"marketCap":13247885603},{"date":"2026-01-30","current":-53.001116,"twenty":-43.304049,"median":-17.016336,"eighty":-10.177655,"marketCap":13586412084},{"date":"2026-02-06","current":-52.748369,"twenty":-43.896106,"median":-17.042828,"eighty":-10.276361,"marketCap":13521622327},{"date":"2026-02-13","current":-51.674193,"twenty":-45.89007,"median":-17.08842,"eighty":-10.365331,"marketCap":13246265859},{"date":"2026-02-20","current":-52.536693,"twenty":-46.437268,"median":-17.113581,"eighty":-10.415699,"marketCap":13467360905},{"date":"2026-02-27","current":-34.265449,"twenty":-46.808807,"median":-17.154283,"eighty":-10.419492,"marketCap":13055136075},{"date":"2026-03-06","current":-32.554417,"twenty":-46.808807,"median":-17.180856,"eighty":-10.419492,"marketCap":12415831546},{"date":"2026-03-13","current":-31.332977,"twenty":-46.808807,"median":-17.209871,"eighty":-10.419492,"marketCap":11949990075},{"date":"2026-03-20","current":-30.891179,"twenty":-46.808807,"median":-17.218631,"eighty":-10.419492,"marketCap":11781494224},{"date":"2026-03-27","current":-32.155933,"twenty":-46.808807,"median":-17.24834,"eighty":-10.419492,"marketCap":12263854896},{"date":"2026-04-02","current":-32.541423,"twenty":-46.808807,"median":-17.287579,"eighty":-10.419492,"marketCap":12410875786},{"date":"2026-04-10","current":-33.104499,"twenty":-46.808807,"median":-17.33251,"eighty":-10.419492,"marketCap":12625625400},{"date":"2026-04-17","current":-32.597731,"twenty":-46.808807,"median":-17.370954,"eighty":-10.419492,"marketCap":12432350747},{"date":"2026-04-24","current":-32.090963,"twenty":-46.808807,"median":-17.417852,"eighty":-10.419492,"marketCap":12239076094},{"date":"2026-05-01","current":-37.78562,"twenty":-46.808807,"median":-17.460406,"eighty":-10.419492,"marketCap":12355028686},{"date":"2026-05-08","current":-38.422456,"twenty":-46.808807,"median":-17.499692,"eighty":-10.425443,"marketCap":12563259507},{"date":"2026-05-15","current":-38.250612,"twenty":-46.808807,"median":-17.54086,"eighty":-10.441583,"marketCap":12507070238},{"date":"2026-05-22","current":-38.301154,"twenty":-46.808807,"median":-17.626193,"eighty":-10.45769,"marketCap":12523596493},{"date":"2026-05-29","current":-39.084564,"twenty":-46.821444,"median":-17.65446,"eighty":-10.515842,"marketCap":12779753455},{"date":"2026-06-05","current":-37.972628,"twenty":-46.808807,"median":-17.690774,"eighty":-10.584827,"marketCap":12416175832},{"date":"2026-06-12","current":-37.31052,"twenty":-46.808807,"median":-17.738974,"eighty":-10.668419,"marketCap":12199681883},{"date":"2026-06-18","current":-37.558179,"twenty":-46.808807,"median":-17.769888,"eighty":-10.69486,"marketCap":12280660536},{"date":"2026-06-26","current":-39.595044,"twenty":-46.821444,"median":-17.818766,"eighty":-10.726786,"marketCap":12946668637},{"date":"2026-07-02","current":-40.024656,"twenty":-46.821444,"median":-17.854581,"eighty":-10.726786,"marketCap":13087141809},{"date":"2026-07-10","current":-32.483705,"twenty":-46.821444,"median":-17.871767,"eighty":-10.726786,"marketCap":10621424474},{"date":"2026-07-17","current":-27.621511,"twenty":-46.821444,"median":-17.880886,"eighty":-10.979464,"marketCap":9031598685},{"date":"2026-07-24","current":-28.23813,"twenty":-46.821444,"median":-17.925673,"eighty":-11.109046,"marketCap":9233219003},{"date":"2026-07-31","current":-15.666504,"twenty":-46.83029,"median":-17.93492,"eighty":-11.257113,"marketCap":8854300676},{"date":"2026-08-07","current":-16.022293,"twenty":-46.83029,"median":-17.93492,"eighty":-11.326236,"marketCap":9055383705},{"date":"2026-08-14","current":-16.42807,"twenty":-46.83029,"median":-17.93492,"eighty":-11.457268,"marketCap":9284718070},{"date":"2026-08-21","current":-17.277849,"twenty":-46.83029,"median":-17.93492,"eighty":-11.52511,"marketCap":9764990760},{"date":"2026-08-28","current":-18.356979,"twenty":-46.83029,"median":-17.973741,"eighty":-11.565738,"marketCap":10374887222},{"date":"2026-09-04","current":-17.092603,"twenty":-46.83029,"median":-17.982683,"eighty":-11.643516,"marketCap":9660294637},{"date":"2026-09-11","current":-16.363381,"twenty":-46.83029,"median":-17.982683,"eighty":-11.688179,"marketCap":9248157519},{"date":"2026-09-15","current":-15.125468,"twenty":-46.83029,"median":-17.982683,"eighty":-11.712128,"marketCap":8548521523}],"updateTime":1789564516801},"$inf$@#url:\"https://stock-news.skytigris.cn/v2/news/list\",params:#symbols:\"IONS\",pageSize:20,pageCount:2,lang_content:\"en\",edition:\"fundamental\",,,undefined,":[{"items":[{"id":"1170767998","title":"Movement Alert｜Ionis Pharmaceuticals Falls 9.78% Overnight, Partner Novartis Pelacarsen Phase 3 Cardiovascular Outcomes Trial Fails to Meet Primary Endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=1170767998","media":"Market Focus","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1170767998?lang=en_us&edition=fundamental","pubTime":"2026-09-08 08:21","pubTimestamp":1788826911,"startTime":"0","endTime":"0","summary":"On September 8, Ionis Pharmaceuticals fell 9.78% overnight, trading at $52.41/share, with turnover of $57,300. The decline was triggered by partner Novartis announcing on September 4 that pelacarsen,...","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":"Novartis Pelacarsen Phase 3 Failure Sinks Ionis","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2665552317","title":"Citi sees limited immediate downside for Ionis after pelacarsen failure","url":"https://stock-news.laohu8.com/highlight/detail?id=2665552317","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665552317?lang=en_us&edition=fundamental","pubTime":"2026-09-07 23:15","pubTimestamp":1788794109,"startTime":"0","endTime":"0","summary":"After Ionis’ (IONS) partner Novartis (NVS) disclosed that the pelacarsen Phase 3 Lp(a)HORIZON study failed to meet its primary endpoint of cardiova...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/citi-sees-limited-immediate-downside-for-ionis-after-pelacarsen-failure-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/citi-sees-limited-immediate-downside-for-ionis-after-pelacarsen-failure-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4578","BK4588","IE00BJJMRZ35.SGD","BK4007","IE00B4R5TH58.HKD","LU0070302665.USD","PPH","BK4585","BK4532","MEDX","LU0211331839.USD","IE00BFTCPJ56.SGD","LU0208291251.USD","IE00BJT1NW94.SGD","IE00B2B36J28.USD","IE0002141913.USD","NVS","IE0009355771.USD","LU0320765489.SGD","BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2665352693","title":"Stocks to Watch: Ionis Pharmaceuticals, Novartis, Corvex","url":"https://stock-news.laohu8.com/highlight/detail?id=2665352693","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665352693?lang=en_us&edition=fundamental","pubTime":"2026-09-05 06:58","pubTimestamp":1788562680,"startTime":"0","endTime":"0","summary":"A heart disease drug made by Ionis Pharmaceuticals and Novartis didn't meet its primary endpoint in a Phase 3 trial. Ionis shares slid 9.5% to $52.60 in after-hours trading on Friday, while Novartis shares were off 4.4% at $153.04.Corvex said it had a loss of $26.3 million in the first half of the year. The stock fell 7.5% to $13.63 after the bell.","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MOVE","PPH","BK4588","BK4578","IONS","LU0070302665.USD","IE00B4R5TH58.HKD","BK4170","IE00BFTCPJ56.SGD","NVS","BK4585","IE00BJT1NW94.SGD","BK4532","IE00BJJMRZ35.SGD","BK4007","IE00B2B36J28.USD","LU0320765489.SGD","LU0208291251.USD","IE0009355771.USD","LU0211331839.USD","IE0002141913.USD","MEDX","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2665354295","title":"Ionis Pharmaceuticals Updates on Novartis Pelacarsen Trial Outcome","url":"https://stock-news.laohu8.com/highlight/detail?id=2665354295","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665354295?lang=en_us&edition=fundamental","pubTime":"2026-09-05 05:47","pubTimestamp":1788558478,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals ( ($IONS) ) has shared an announcement. On September 4, 2026, Ionis Pharmaceuticals reported that its partner Novartis’ Phase...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/ionis-pharmaceuticals-updates-on-novartis-pelacarsen-trial-outcome?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/ionis-pharmaceuticals-updates-on-novartis-pelacarsen-trial-outcome?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2665535175","title":"Novartis announces Phase 3 pelacarsen study did not meet primary endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2665535175","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665535175?lang=en_us&edition=fundamental","pubTime":"2026-09-05 04:55","pubTimestamp":1788555312,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals (IONS) partner Novartis (NVS) announced that the pelacarsen Phase 3 Lp(a)HORIZON study, a pioneering cardiovascular outcomes ...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/novartis-announces-phase-3-pelacarsen-study-did-not-meet-primary-endpoint-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/novartis-announces-phase-3-pelacarsen-study-did-not-meet-primary-endpoint-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["NVS","BK4588","IE00B4R5TH58.HKD","PPH","IE00BFTCPJ56.SGD","IE00BJT1NW94.SGD","LU0320765489.SGD","MEDX","IONS","LU0070302665.USD","LU0211331839.USD","IE00BJJMRZ35.SGD","LU0208291251.USD","IE0009355771.USD","BK4007","BK4585","BK4578","IE00B2B36J28.USD","BK4532","IE0002141913.USD","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2665418351","title":"Ionis-Novartis Heart Drug Misses Main Goal of Late-Stage Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2665418351","media":"Reuters","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665418351?lang=en_us&edition=fundamental","pubTime":"2026-09-05 04:51","pubTimestamp":1788555074,"startTime":"0","endTime":"0","summary":"Ionis-Novartis heart drug misses main goal of late-stage trialSept 4 (Reuters)-Ionis PharmaceuticalsIONS.Oand partner Novartis'NOVN.Sexperimental drug to lower high levels of a type of fat and protein","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260904:nL4N44W1D6:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2665235141","title":"Novartis Says Pelacarsen Heart Disease Drug Missed Primary Endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2665235141","media":"Dow Jones","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665235141?lang=en_us&edition=fundamental","pubTime":"2026-09-05 04:50","pubTimestamp":1788555000,"startTime":"0","endTime":"0","summary":"Novartis said a heart disease drug did not meet its primary endpoint in a Phase 3 study.The company on Friday said that the drug, pelacarsen, did not reduce the risk of cardiovascular events--including deaths, heart attacks, and strokes--compared to a placebo.The drug did succeed in lowering lipoprotein levels, Novartis said.\"These are not the results we hoped for, but they provide important evidence that advances scientific understanding of the relationship between Lp lowering and cardiovascular outcomes and may help inform future approaches to cardiovascular risk management,\" Chief Medical Officer Shreeram Aradhye said.Pelacarsen was initially discovered and developed by Ionis Pharmaceuticals, before Novartis exercised an option to license development and commercialization rights for the drug in 2019.Shares of Novartis declined 4.4% to $153.00 in after-hours trading on Friday. Ionis shares were flat.","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4578","LU0208291251.USD","IE00B2B36J28.USD","BK4139","LU0320765489.SGD","IE00BJT1NW94.SGD","NVS","BK4532","PPH","IE0002141913.USD","IE00B4R5TH58.HKD","MEDX","BK4007","BK4588","LU0070302665.USD","IONS","LU0211331839.USD","BK4585","IE00BJJMRZ35.SGD","IE00BFTCPJ56.SGD","IE0009355771.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2665351966","title":"Ionis Pharmaceuticals: Buy Rating Backed by FDA Approval of Zanvastro and Strengthened Neurology Pipeline Upside","url":"https://stock-news.laohu8.com/highlight/detail?id=2665351966","media":"TIPRANKS","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665351966?lang=en_us&edition=fundamental","pubTime":"2026-09-05 04:35","pubTimestamp":1788554117,"startTime":"0","endTime":"0","summary":"William Blair analyst Myles Minter has reiterated their bullish stance on IONS stock, giving a Buy rating today. Myles Minter has given his Buy rat...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/ionis-pharmaceuticals-buy-rating-backed-by-fda-approval-of-zanvastro-and-strengthened-neurology-pipeline-upside-ratings-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/ionis-pharmaceuticals-buy-rating-backed-by-fda-approval-of-zanvastro-and-strengthened-neurology-pipeline-upside-ratings-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS","LABU"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1142505378","title":"Movement Alert｜Ionis Pharmaceuticals Falls 9.43% in After-Hours Trading, FDA Approval of Alexander Disease Drug Triggers Sell-the-News Reaction","url":"https://stock-news.laohu8.com/highlight/detail?id=1142505378","media":"Market Focus","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1142505378?lang=en_us&edition=fundamental","pubTime":"2026-09-05 04:34","pubTimestamp":1788554057,"startTime":"0","endTime":"0","summary":"On September 5, Ionis Pharmaceuticals fell 9.43% in after-hours trading, trading at $55.35 per share, with turnover of approximately $2.1 million.On the news front, the FDA on September 4 officially...","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis Falls on Sell-the-News After FDA Approves Zanvastro","news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2665353911","title":"Ionis Pharmaceuticals (IONS) Receives a Rating Update from a Top Analyst","url":"https://stock-news.laohu8.com/highlight/detail?id=2665353911","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665353911?lang=en_us&edition=fundamental","pubTime":"2026-09-05 00:15","pubTimestamp":1788538518,"startTime":"0","endTime":"0","summary":"In a report released today, Yaron Werber from TD Cowen reiterated a Buy rating on Ionis Pharmaceuticals, with a price target of $94.00. According t...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/ionis-pharmaceuticals-ions-receives-a-rating-update-from-a-top-analyst-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/ionis-pharmaceuticals-ions-receives-a-rating-update-from-a-top-analyst-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2665935360","title":"This Biotech Wins a Big FDA Approval. Why Wall Street is Shrugging.","url":"https://stock-news.laohu8.com/highlight/detail?id=2665935360","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665935360?lang=en_us&edition=fundamental","pubTime":"2026-09-05 00:13","pubTimestamp":1788538380,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals has won regulatory approval for a first-of-its kind drug targeting a rare brain disease, but Wall Street is shrugging off the news for a simple reason.Zilganersen, branded as Zan","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4581","PBE","ARWR","IE00B19Z9P08.USD","LU0320765992.SGD","BK4533","BIIB","IONS","BMED","LABU","LU0889565916.HKD","BK4585","IE00B894F039.SGD","BK4139","LU0109394709.USD","LU0234570918.USD","IE00B19Z9Z06.USD","XBI","BK4532","BK4588"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664489358","title":"Analysts’ Opinions Are Mixed on These Healthcare Stocks: cbdMD (YCBD) and Ionis Pharmaceuticals (IONS)","url":"https://stock-news.laohu8.com/highlight/detail?id=2664489358","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664489358?lang=en_us&edition=fundamental","pubTime":"2026-09-04 23:30","pubTimestamp":1788535809,"startTime":"0","endTime":"0","summary":"Companies in the Healthcare sector have received a lot of coverage today as analysts weigh in on cbdMD (YCBD) and Ionis Pharmaceuticals (IONS). cbd...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-opinions-are-mixed-on-these-healthcare-stocks-cbdmd-ycbd-and-ionis-pharmaceuticals-ions-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-opinions-are-mixed-on-these-healthcare-stocks-cbdmd-ycbd-and-ionis-pharmaceuticals-ions-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["HCSG","XLV","XBI","BK4588","YCBD","BK4585","LABU","BK4139","BK4137","BK4007","LU0029874061.USD","LU0128526141.USD","IONS","BK4581"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664849358","title":"Ionis Pharmaceuticals' Zanvastro Approval Sets Path for Independent Neurology Business, Oppenheimer Says","url":"https://stock-news.laohu8.com/highlight/detail?id=2664849358","media":"MT Newswires Live","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664849358?lang=en_us&edition=fundamental","pubTime":"2026-09-04 23:10","pubTimestamp":1788534632,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals (IONS) has established its first independently commercialized neurology asset with the approval of Zanvastro for Alexander disease, Oppenheimer said in a Friday note.The US Food ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664337209","title":"Ionis Pharmaceuticals Exec Says Zanvastro Will be Available at List Price of $285,000 Per Dose","url":"https://stock-news.laohu8.com/highlight/detail?id=2664337209","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664337209?lang=en_us&edition=fundamental","pubTime":"2026-09-04 22:12","pubTimestamp":1788531162,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260904:nFWN44W0FZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664333917","title":"U.S. Stocks on the MOVE-Lululemon Athletica, Adobe, Ionis Pharmaceuticals","url":"https://stock-news.laohu8.com/highlight/detail?id=2664333917","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664333917?lang=en_us&edition=fundamental","pubTime":"2026-09-04 19:36","pubTimestamp":1788521808,"startTime":"0","endTime":"0","summary":"BUZZ-U.S. STOCKS ON THE MOVE-Lululemon Athletica, Adobe, Ionis PharmaceuticalsSeptember 4 (Reuters)-Futures tracking the tech-heavy Nasdaq 100 and the benchmark S&P 500 indexes rose on Friday ahead of","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260904:nL6N44W0NC:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0057025933.USD","LU1235294995.USD","LU1548497426.USD","LU2089283258.USD","BK4567","ADBG","LU2125154935.USD","LU0081259029.USD","LU0109391861.USD","LU0868494617.USD","SGXZ51526630.SGD","LU0965509101.SGD","LU0511384066.AUD","LU0348723411.USD","LU1674673428.USD","LU0345774631.USD","SG9999015945.SGD","LU1623119135.USD","LU1261432733.SGD","SG9999015978.USD","LU0868494708.USD","LU0314104364.USD","SGXZ99366536.SGD","LU2237438978.USD","BK4139","LU0082616367.USD","TTD","SG9999001424.SGD","LU0061474960.USD","BK4543","BK4097","LU0965509010.AUD","LU0557290698.USD","LU2458330169.SGD","LU2210150020.SGD","BK4534","LU1778281490.HKD","IE00BFXG0V08.USD","BK4504","LU0792757196.USD","IE00B5TLWC47.USD","LU0957791311.USD","LU0672654240.SGD","LU2317271919.USD","IE00BQXX3C00.GBP","LU1720051017.SGD","BK4527","LU1720051108.HKD","LU2125154778.USD","LU0157215616.USD","BK4202","LU0106261372.USD","LU0158827948.USD","BK4560","SG9999000418.SGD","SGXZ81514606.USD","LU0345774391.USD","ADBU","LULU","LU0006306889.USD","TTDU","LU1674673691.USD","LU1267930730.SGD","LU2095319765.USD","LU0889565833.HKD","ZS","LU2458330243.SGD","BK4009","IE00BQXX3F31.USD","ADBE","LU0170899867.USD","LU0965509283.SGD","LU1267930813.SGD","LU2125909759.SGD","LU0289739343.SGD","LU0320765059.SGD","IE00BYQQ9H92.USD","LU0889566641.SGD","BK4585","LU1119994496.HKD","BK4613","LU1691799644.USD","LU0342679015.USD","IE00B19Z9505.USD","LU0109392836.USD","LU2360032135.SGD","BK4548","LU1496350502.SGD","LU2286300806.USD","LU0234572021.USD","LU1366333091.USD","BK4533","LU0069063385.USD","LU2125909916.SGD","BK4588","LU0861579265.USD","LU1712237335.SGD","SG9999015986.USD","LU1815333072.USD","IE00BQXX3D17.EUR","BK4566","LU1084165304.USD","IONS","BK4023","LU2236285917.USD","BK4581","LU0390134368.USD","LULG","LU2023251221.USD","LU0289961442.SGD","LU1046421795.USD","LU1633808545.USD","BK4554","LU2357305700.SGD","LU2210149790.SGD","LU1803068979.SGD","LU1823568750.SGD","LU0942090050.USD","IE0009356076.USD","LU0198837287.USD","BK4592","LU0719512351.SGD","LU2089284900.SGD","SG9999015952.SGD","LU0823411888.USD","LU0234570918.USD","LU0472753341.HKD","LU1923622291.USD","LU0708995401.HKD","BK4528"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664339557","title":"Ionis Pharmaceuticals (IONS) Receives a Hold from BMO Capital","url":"https://stock-news.laohu8.com/highlight/detail?id=2664339557","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664339557?lang=en_us&edition=fundamental","pubTime":"2026-09-04 19:16","pubTimestamp":1788520564,"startTime":"0","endTime":"0","summary":"In a report released today, David Lebowitz from BMO Capital maintained a Hold rating on Ionis Pharmaceuticals, with a price target of $61.00. In ad...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/ionis-pharmaceuticals-ions-receives-a-hold-from-bmo-capital-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/ionis-pharmaceuticals-ions-receives-a-hold-from-bmo-capital-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664357653","title":"Ionis Pharmaceuticals Price Target Maintained with a $115.00/Share by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2664357653","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664357653?lang=en_us&edition=fundamental","pubTime":"2026-09-04 18:17","pubTimestamp":1788517020,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/IONS/analyst-ratings","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664335632","title":"Ionis Pharma up After US FDA Approves Rare Brain Disorder Treatment","url":"https://stock-news.laohu8.com/highlight/detail?id=2664335632","media":"Reuters","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664335632?lang=en_us&edition=fundamental","pubTime":"2026-09-04 18:00","pubTimestamp":1788516050,"startTime":"0","endTime":"0","summary":"BUZZ-Ionis Pharma up after US FDA approves rare brain disorder treatment** Shares of Ionis PharmaceuticalsIONS.Orise 1.5% to $59 premarket** U.S. FDA late on Thursdayapprovedco's therapy to treat a ra","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260904:nL4N44W0PW:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664338703","title":"Ionis Pharmaceuticals Gets FDA Approval for Alexander Disease Treatment","url":"https://stock-news.laohu8.com/highlight/detail?id=2664338703","media":"MT Newswires Live","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664338703?lang=en_us&edition=fundamental","pubTime":"2026-09-04 16:23","pubTimestamp":1788510190,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals  said late Thursday the US Food and Drug Administration approved zanvastrotm, or zilganersen, to treat Alexander disease in pediatric and adult patients.The treatment will be available in the US in the coming weeks, according to the company.A zanvastrotm trial met its primary endpoint in individuals aged at least five years, with the 50-milligram dose showing \"statistically significant and clinically meaningful\" stabilization of gait speed, compared with control at week 61, Ionis said.Alexander disease is an ultra-rare, progressive and often fatal neurological disorder that can affect motor, cognitive, autonomic and gastrointestinal function.The company's shares were up 1.5% in premarket activity Friday.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["IONS","BK4588","BK4139","LABU","BK4585"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664840383","title":"U.S. Research Roundup-Ciena Corp, Docusign, Snowflake","url":"https://stock-news.laohu8.com/highlight/detail?id=2664840383","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664840383?lang=en_us&edition=fundamental","pubTime":"2026-09-04 15:08","pubTimestamp":1788505701,"startTime":"0","endTime":"0","summary":"U.S. RESEARCH ROUNDUP-Ciena Corp, Docusign, SnowflakeSept 4 (Reuters)-Wall Street securities analysts revised their ratings and price targets on several U.S.-listed companies, including Ciena...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260904:nL4N44W0I0:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","PCAR","TSN","CLYM","HP","BLTE","BP","ALGS","NETL","RTH","COST","ASAN","AMBA","PTEN","SNOW","SNOY","CLIM","IOT","SAIA","WPC","AKAM","COTG","PATH","PL","NNN","O","LEN","VSXY","CIEN","FSTA","DNTH","PHM","GWRE","ZS","DOCU","ORA","FERG","AQWA","DAT","FCPT","SFNC","CTRI","PCG","OBT","CBNK","FLNC","INDS","SRHR","MARS","CURV"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":10,"pageCount":2,"totalSize":200,"code":"91000000","status":"200"}]}}