US StockDetailed Quotes

Provided by Tiger Trade Technology Pte. Ltd.

Ionis Pharmaceuticals

44.84

-2.4100-5.10%

Post-market: 44.910.0700+0.16%19:56 EDT

Volume:7.96M

Turnover:363.93M

Market Cap:7.45B

PE:-12.89

High:47.59

Open:47.38

Low:44.66

Close:47.25

52wk High:86.74

52wk Low:44.66

Shares:166.18M

Float Shares:161.92M

Volume Ratio:1.89

T/O Rate:4.91%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-3.4800

EPS(LYR):-2.3812

ROE:-105.50%

ROA:-12.42%

PB:16.95

PE(LYR):-18.83

Loading ...

Overview Company News Filings

Movement Alert｜Ionis Pharmaceuticals Falls 20.03% in Regular Trading, Core Pipeline Drug Eplontersen Fails Phase 3 Cardiac Trial Primary Endpoint

Ionis Pharmaceuticals (IONS) Stock Slammed by Phase 3 Trial Results

Ionis Pharmaceuticals falls -17.6%

Exchange-Traded Funds Higher, Equity Futures Mixed Pre-Bell Thursday as Chip Stocks Rebound Despite US-Iran Tensions

MT Newswires Live

Astrazeneca and Ionis Stocks Sink on Trial Miss and Analysts See an Overreaction

Ionis Pharmaceuticals Shares Sink After Late-stage Trial Failed to Meet Primary Goal

U.S. Stocks on the Move-levi, Ionis Pharmaceuticals, Gloo Holdings

S&P 500 Futures Climb in Premarket Trading; Alnylam Pharmaceuticals, Bridgebio Pharma Lead

Schwab Strategists Warn of a Major Market Shift: the Era of Easy Index Gains is Officially Over.

Major Drugmaker Loses $27 Billion in Market Value After Failed Trial

AstraZeneca says CARDIO-TTRansform trial did not meet primary efficacy endpoint

Tech Rebound Lifts European Shares After Three-day Slide

Ionis Pharmaceuticals Shares Fall 13.8% Premarket After Drug Made in Partnership with Astrazeneca Fails Late-stage Heart Disease Trial

THOMSON REUTERS

Movement Alert｜Ionis Pharmaceuticals Falls 14.75% in Pre-Market Trading, Phase 3 ATTR-CM Trial for Eplontersen Fails Primary Endpoint

Astrazeneca Top Loser on FTSE 100 After Heart Disease Drug Fails Late-stage Trial

Astrazeneca Shares Set for Their Biggest One-day Fall Since March 2020

THOMSON REUTERS

Astrazeneca Shares Down 9% After Late-stage Trial Miss for Nerve Disease Drug Wainua

THOMSON REUTERS

European Shares Gain as Tech Stocks Rebound; Middle East in Focus

Astrazeneca's Wainua Fails Key Heart Disease Trial, Shares Tumble

Ionis Says Phase 3 Eplontersen Trial in Attr-cm Misses Primary Endpoint

{"basename":"","ssrTDKData":{"titleTemplate":"%s - Tiger Brokers","title":"Easy breezy. No more feesies.","description":"Tiger Trade is a mobile trading app offering real time data, low commission fees and a free demo account. Download now to start investing in ETFs, options and the global share market.","keywords":"Tiger Brokers,U.S. stock trading,Hong Kong stock trading,trading U.S. stocks,stock information,stock prices,U.S. stock quotes,U.S. stock trading,Hong Kong stock trading,IPO trading,buying U.S. stocks,global investment","social":{"ogDescription":"Tiger Trade is a mobile trading app offering real time data, low commission fees and a free demo account. Download now to start investing in ETFs, options and the global share market.","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.0a0bd8dc.png","ogUrl":"https://www.thetigerbrokers.com/stock/IONS/news?page=7"},"companyName":"Tiger Brokers"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"NZL","license":"TBKIWI","edition":"fundamental","symbol":"IONS","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"IONS\",,,,,undefined,":{"symbol":"IONS","market":"US","secType":"STK","nameCN":"Ionis Pharmaceuticals","latestPrice":44.84,"timestamp":1789588800000,"preClose":47.25,"halted":0,"volume":7958213,"hourTrading":{"tag":"盘后","latestPrice":44.91,"preClose":44.84,"latestTime":"19:56 EDT","volume":595190,"amount":26688938.3001,"timestamp":1789602998592,"change":0.07,"changeRate":0.001561,"amplitude":0.00959},"delay":0,"changeRate":-0.051005291005290936,"floatShares":161921007,"shares":166184322,"eps":-3.48,"marketStatus":"Not Yet Opened","change":-2.41,"latestTime":"09-16 16:00:00 EDT","open":47.38,"high":47.59,"low":44.66,"amount":363934730.82123,"amplitude":0.062011,"askPrice":0,"askSize":0,"bidPrice":0,"bidSize":0,"shortable":3,"etf":0,"ttmEps":-3.48,"tradingStatus":0,"nextMarketStatus":{"tag":"Pre-Mkt","tradingStatus":1,"beginTime":1789632000000},"marketStatusCode":0,"adr":0,"adrRate":0,"exchange":"NASDAQ","adjPreClose":47.25,"preHourTrading":{"tag":"盘前","latestPrice":47.21,"preClose":47.25,"latestTime":"09:29 EDT","volume":7343,"amount":347911.54560400004,"timestamp":1789565399999,"change":-0.04,"changeRate":-0.000847,"amplitude":0.01037},"postHourTrading":{"tag":"盘后","latestPrice":44.91,"preClose":44.84,"latestTime":"19:56 EDT","volume":595190,"amount":26688938.3001,"timestamp":1789602998592,"change":0.07,"changeRate":0.001561,"amplitude":0.00959},"volumeRatio":1.889588,"impliedVol":0.5561,"impliedVolPercentile":0.9402},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"IONS\",,,,,undefined,":{"symbol":"IONS","floatShares":161921007,"roa":"-12.42%","roe":"-105.50%","lyrEps":-2.38125,"volumeRatio":1.889588,"shares":166184322,"dividePrice":0,"high":47.59,"amplitude":0.062011,"preClose":47.25,"low":44.66,"week52Low":44.66,"pbRate":"16.95","psRate":"8.53","week52High":86.74,"institutionHeld":0.92,"latestPrice":44.84,"eps":-3.48,"divideRate":0,"volume":7958213,"delay":0,"ttmEps":-3.48,"open":47.38,"prevYearClose":79.11,"prevWeekClose":54.21,"prevMonthClose":60.36,"prevQuarterClose":79.29,"fiveDayClose":56.02,"twentyDayClose":59.62,"sixtyDayClose":75.89},"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/IONS\",params:#limit:5,,,undefined,":[{"market":"US","date":"2026-07-29","symbol":"IONS","fiscalQuarterEnding":"2026/06","expectedEps":-1.09,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1785297600000,"reportTimeType":"pre","actualEps":-0.7},{"market":"US","date":"2026-04-29","symbol":"IONS","fiscalQuarterEnding":"2026/03","expectedEps":-0.89,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1777435200000,"reportTimeType":"pre","actualEps":-0.56},{"market":"US","date":"2026-02-25","symbol":"IONS","fiscalQuarterEnding":"2025/12","expectedEps":-1.31,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1771995600000,"reportTimeType":"pre","actualEps":-1.41},{"market":"US","date":"2025-10-29","symbol":"IONS","fiscalQuarterEnding":"2025/09","expectedEps":-1.23,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1761710400000,"reportTimeType":"pre","actualEps":-0.8},{"market":"US","date":"2025-07-30","symbol":"IONS","fiscalQuarterEnding":"2025/06","expectedEps":-0.11,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1753848000000,"reportTimeType":"pre","actualEps":0.7}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"IONS\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"IONS\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0.2308,"buy":0.5385,"hold":0.2308,"sell":0,"strongSell":0,"meanLabel":"BUY","meanPercent":0.5385,"analysts":26,"updateTime":1787112000000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/IONS\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"IONS","date":"2026-09-15","current":-12.885057,"percent":0.719284,"low":-1664.931905,"twenty":-46.83029,"median":-17.982683,"eighty":-11.712128,"high":882.260453,"avg":-65.18325,"sd":366.233599,"marketCap":8548521523},"quantilePoints":[{"date":"2021-09-17","current":-9.553748,"twenty":-43.823694,"median":22.105712,"eighty":90.484478,"marketCap":5252105842},{"date":"2021-09-24","current":-9.294428,"twenty":-43.823694,"median":21.894477,"eighty":89.822908,"marketCap":5109546667},{"date":"2021-10-01","current":-8.61917,"twenty":-43.823694,"median":21.739571,"eighty":88.160122,"marketCap":4738328221},{"date":"2021-10-08","current":-8.752681,"twenty":-43.823694,"median":21.475528,"eighty":87.371554,"marketCap":4811725024},{"date":"2021-10-15","current":-9.012001,"twenty":-43.823694,"median":21.145012,"eighty":86.264015,"marketCap":4954284199},{"date":"2021-10-22","current":-7.815535,"twenty":-43.823694,"median":21.004285,"eighty":84.663252,"marketCap":4296535927},{"date":"2021-10-29","current":-8.182691,"twenty":-43.823694,"median":20.82218,"eighty":83.19244,"marketCap":4498377135},{"date":"2021-11-05","current":-7.827936,"twenty":-43.823694,"median":20.669316,"eighty":82.070133,"marketCap":4757365405},{"date":"2021-11-12","current":-7.595584,"twenty":-43.823694,"median":20.616507,"eighty":76.079084,"marketCap":4616155390},{"date":"2021-11-19","current":-7.432938,"twenty":-43.823694,"median":20.366546,"eighty":75.49578,"marketCap":4517308379},{"date":"2021-11-26","current":-6.749823,"twenty":-43.823694,"median":20.294106,"eighty":74.547727,"marketCap":4102150935},{"date":"2021-12-03","current":-6.131767,"twenty":-43.823694,"median":20.173015,"eighty":74.030875,"marketCap":3726532295},{"date":"2021-12-10","current":-6.847411,"twenty":-43.823694,"median":20.114106,"eighty":72.607318,"marketCap":4161459142},{"date":"2021-12-17","current":-7.542143,"twenty":-43.823694,"median":20.025743,"eighty":70.436541,"marketCap":4583677086},{"date":"2021-12-23","current":-7.600231,"twenty":-43.823694,"median":19.891562,"eighty":60.214071,"marketCap":4618979590},{"date":"2021-12-31","current":-7.070469,"twenty":-43.823694,"median":19.796653,"eighty":53.012098,"marketCap":4297020756},{"date":"2022-01-07","current":-7.058851,"twenty":-43.611673,"median":19.749198,"eighty":51.923862,"marketCap":4289960255},{"date":"2022-01-14","current":-7.686201,"twenty":-43.611673,"median":19.64938,"eighty":51.147099,"marketCap":4671227296},{"date":"2022-01-21","current":-6.942675,"twenty":-43.611673,"median":19.61175,"eighty":50.934296,"marketCap":4219355248},{"date":"2022-01-28","current":-7.360909,"twenty":-43.611673,"median":19.468798,"eighty":50.847883,"marketCap":4473533275},{"date":"2022-02-04","current":-7.319085,"twenty":-43.611673,"median":19.28882,"eighty":50.5876,"marketCap":4448115472},{"date":"2022-02-11","current":-7.639731,"twenty":-43.611673,"median":19.164904,"eighty":50.143461,"marketCap":4642985293},{"date":"2022-02-18","current":-7.497996,"twenty":-43.611673,"median":18.965356,"eighty":49.908881,"marketCap":4556847184},{"date":"2022-02-25","current":-157.459445,"twenty":-44.533501,"median":18.77393,"eighty":49.713145,"marketCap":4502867744},{"date":"2022-03-04","current":-160.035874,"twenty":-45.829592,"median":18.155386,"eighty":49.32903,"marketCap":4576545882},{"date":"2022-03-11","current":-159.49086,"twenty":-46.633425,"median":-6.144547,"eighty":48.69515,"marketCap":4560960122},{"date":"2022-03-18","current":-174.652153,"twenty":-47.12015,"median":-6.881102,"eighty":48.427938,"marketCap":4994527626},{"date":"2022-03-25","current":-181.687786,"twenty":-47.927671,"median":-7.000763,"eighty":48.265452,"marketCap":5195725619},{"date":"2022-04-01","current":-192.736702,"twenty":-48.230031,"median":-7.040263,"eighty":47.833218,"marketCap":5511691480},{"date":"2022-04-08","current":-198.781401,"twenty":-48.689101,"median":-7.082087,"eighty":47.228668,"marketCap":5684551727},{"date":"2022-04-14","current":-202.992871,"twenty":-49.716018,"median":-7.119262,"eighty":46.918857,"marketCap":5804987145},{"date":"2022-04-22","current":-206.852389,"twenty":-50.435043,"median":-7.237762,"eighty":46.570634,"marketCap":5915357781},{"date":"2022-04-29","current":-182.216483,"twenty":-51.591015,"median":-7.300497,"eighty":46.245658,"marketCap":5210844764},{"date":"2022-05-06","current":-1322.183946,"twenty":-128.214398,"median":-7.341159,"eighty":45.925265,"marketCap":5147262100},{"date":"2022-05-13","current":-1314.170709,"twenty":-130.326929,"median":-7.37485,"eighty":45.90793,"marketCap":5116066572},{"date":"2022-05-20","current":-1438.375868,"twenty":-130.86667,"median":-7.37485,"eighty":45.90793,"marketCap":5599597254},{"date":"2022-05-27","current":-1370.6276,"twenty":-132.625178,"median":-7.37485,"eighty":45.90793,"marketCap":5335853246},{"date":"2022-06-03","current":-1316.720376,"twenty":-134.128325,"median":-7.37485,"eighty":45.90793,"marketCap":5125992422},{"date":"2022-06-10","current":-1266.091293,"twenty":-137.45382,"median":-7.37485,"eighty":45.90793,"marketCap":4928893405},{"date":"2022-06-17","current":-1284.303193,"twenty":-139.005646,"median":-7.37485,"eighty":45.90793,"marketCap":4999792332},{"date":"2022-06-24","current":-1429.634156,"twenty":-139.862338,"median":-7.360909,"eighty":45.909339,"marketCap":5565565769},{"date":"2022-07-01","current":-1386.289834,"twenty":-141.353878,"median":-7.360909,"eighty":45.909339,"marketCap":5396826323},{"date":"2022-07-08","current":-1353.144176,"twenty":-142.456573,"median":-7.360909,"eighty":45.909339,"marketCap":5267790276},{"date":"2022-07-15","current":-1431.819584,"twenty":-143.808127,"median":-7.360909,"eighty":45.909339,"marketCap":5574073640},{"date":"2022-07-22","current":-1387.746786,"twenty":-144.656772,"median":-7.360909,"eighty":45.909339,"marketCap":5402498237},{"date":"2022-07-29","current":-1368.077934,"twenty":-146.022974,"median":-7.360909,"eighty":45.909339,"marketCap":5325927396},{"date":"2022-08-05","current":-1664.567667,"twenty":-147.819198,"median":-7.360909,"eighty":45.909339,"marketCap":6480161927},{"date":"2022-08-12","current":-222.342663,"twenty":-148.698169,"median":-7.360909,"eighty":45.909339,"marketCap":6259613005},{"date":"2022-08-19","current":-221.838485,"twenty":-149.407406,"median":-7.360909,"eighty":45.909339,"marketCap":6245418872},{"date":"2022-08-26","current":-213.519542,"twenty":-149.883165,"median":-7.360909,"eighty":45.909339,"marketCap":6011215664},{"date":"2022-09-02","current":-218.006729,"twenty":-150.165357,"median":-7.360909,"eighty":45.909339,"marketCap":6137543455},{"date":"2022-09-09","current":-236.157151,"twenty":-151.092649,"median":-7.360909,"eighty":45.909339,"marketCap":6648532271},{"date":"2022-09-16","current":-233.585841,"twenty":-153.529951,"median":-7.360909,"eighty":45.909339,"marketCap":6576142189},{"date":"2022-09-23","current":-217.956312,"twenty":-156.46647,"median":-7.360909,"eighty":45.909339,"marketCap":6136124041},{"date":"2022-09-30","current":-222.998095,"twenty":-157.969129,"median":-7.360909,"eighty":45.909339,"marketCap":6278065379},{"date":"2022-10-07","current":-231.569128,"twenty":-159.577078,"median":-7.360909,"eighty":45.909339,"marketCap":6519365654},{"date":"2022-10-14","current":-233.737095,"twenty":-160.082841,"median":-7.360909,"eighty":45.909339,"marketCap":6580400429},{"date":"2022-10-21","current":-226.62818,"twenty":-160.43291,"median":-7.360909,"eighty":45.909339,"marketCap":6380263143},{"date":"2022-10-28","current":-224.913973,"twenty":-161.94987,"median":-7.360909,"eighty":45.909339,"marketCap":6332003088},{"date":"2022-11-04","current":-209.486115,"twenty":-162.370971,"median":-7.360909,"eighty":45.909339,"marketCap":5897662593},{"date":"2022-11-11","current":839.185498,"twenty":-162.756411,"median":-7.319085,"eighty":46.031035,"marketCap":6143677032},{"date":"2022-11-18","current":836.080997,"twenty":-162.756411,"median":-7.284232,"eighty":46.34415,"marketCap":6120948978},{"date":"2022-11-25","current":806.394204,"twenty":-162.756411,"median":-7.219174,"eighty":46.64061,"marketCap":5903611964},{"date":"2022-12-02","current":782.334319,"twenty":-162.756411,"median":-7.102998,"eighty":47.141347,"marketCap":5727469547},{"date":"2022-12-09","current":727.617484,"twenty":-162.756411,"median":-7.058851,"eighty":47.387939,"marketCap":5326887600},{"date":"2022-12-16","current":750.125118,"twenty":-162.756411,"median":-7.014704,"eighty":48.047842,"marketCap":5491665989},{"date":"2022-12-23","current":740.423552,"twenty":-162.756411,"median":-6.972881,"eighty":48.293594,"marketCap":5420640821},{"date":"2022-12-30","current":732.85633,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5365241190},{"date":"2023-01-06","current":786.214945,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5755879614},{"date":"2023-01-13","current":773.214846,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5660705889},{"date":"2023-01-20","current":790.871697,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5789971695},{"date":"2023-01-27","current":776.513379,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5684854446},{"date":"2023-02-03","current":793.976198,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5812699749},{"date":"2023-02-10","current":756.722183,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5539963104},{"date":"2023-02-17","current":748.96093,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5483142969},{"date":"2023-02-24","current":-18.915876,"twenty":-162.756411,"median":-6.942675,"eighty":48.318169,"marketCap":5102028010},{"date":"2023-03-03","current":-19.398181,"twenty":-162.756411,"median":-7.010057,"eighty":48.167441,"marketCap":5232116143},{"date":"2023-03-10","current":-17.998968,"twenty":-162.756411,"median":-7.047233,"eighty":47.522459,"marketCap":4854717602},{"date":"2023-03-17","current":-18.645574,"twenty":-162.756411,"median":-7.096027,"eighty":47.151665,"marketCap":5029121473},{"date":"2023-03-24","current":-17.993668,"twenty":-162.756411,"median":-7.188968,"eighty":46.719576,"marketCap":4853288062},{"date":"2023-03-31","current":-18.942377,"twenty":-162.739653,"median":-7.283071,"eighty":46.447558,"marketCap":5109175709},{"date":"2023-04-06","current":-19.392881,"twenty":-162.739653,"median":-7.309791,"eighty":46.139197,"marketCap":5230686603},{"date":"2023-04-14","current":-19.906986,"twenty":-162.756411,"median":-7.388791,"eighty":45.881909,"marketCap":5369351977},{"date":"2023-04-21","current":-19.158378,"twenty":-162.756411,"median":-7.484055,"eighty":45.586713,"marketCap":5167435947},{"date":"2023-04-28","current":-18.691747,"twenty":-162.756411,"median":-7.542143,"eighty":45.238708,"marketCap":5041575343},{"date":"2023-05-05","current":-15.654507,"twenty":-162.722895,"median":-7.581643,"eighty":45.096531,"marketCap":5148454369},{"date":"2023-05-12","current":-15.484823,"twenty":-162.005118,"median":-7.581643,"eighty":45.096531,"marketCap":5092648444},{"date":"2023-05-19","current":-15.937315,"twenty":-160.611822,"median":-7.581643,"eighty":45.096531,"marketCap":5241464245},{"date":"2023-05-26","current":-17.042442,"twenty":-160.205418,"median":-7.581643,"eighty":45.096531,"marketCap":5604918222},{"date":"2023-06-02","current":-18.682728,"twenty":-159.773437,"median":-7.581643,"eighty":45.096531,"marketCap":6144375503},{"date":"2023-06-09","current":-18.121463,"twenty":-159.192484,"median":-7.581643,"eighty":45.096531,"marketCap":5959786673},{"date":"2023-06-16","current":-18.138866,"twenty":-156.985977,"median":-7.581643,"eighty":45.096531,"marketCap":5965510357},{"date":"2023-06-23","current":-17.925673,"twenty":-155.435521,"median":-7.578157,"eighty":45.109315,"marketCap":5895395220},{"date":"2023-06-30","current":-17.886515,"twenty":-151.740635,"median":-7.574672,"eighty":45.122099,"marketCap":5882516929},{"date":"2023-07-07","current":-18.169323,"twenty":-150.657265,"median":-7.574672,"eighty":45.122099,"marketCap":5975526805},{"date":"2023-07-14","current":-18.560903,"twenty":-150.083568,"median":-7.574672,"eighty":45.122099,"marketCap":6104309711},{"date":"2023-07-21","current":-17.821251,"twenty":-149.641501,"median":-7.574672,"eighty":45.122099,"marketCap":5861053112},{"date":"2023-07-28","current":-16.750932,"twenty":-149.090615,"median":-7.574672,"eighty":45.122099,"marketCap":5509046504},{"date":"2023-08-04","current":-17.151214,"twenty":-148.303568,"median":-7.574672,"eighty":45.122099,"marketCap":5640691252},{"date":"2023-08-11","current":-18.467972,"twenty":-148.00823,"median":-7.574672,"eighty":45.122099,"marketCap":5707249602},{"date":"2023-08-18","current":-18.147959,"twenty":-147.735407,"median":-7.574672,"eighty":45.122099,"marketCap":5608354519},{"date":"2023-08-25","current":-18.463334,"twenty":-145.579013,"median":-7.574672,"eighty":45.122099,"marketCap":5705816340},{"date":"2023-09-01","current":-18.676675,"twenty":-145.219114,"median":-7.574672,"eighty":45.122099,"marketCap":5771746396},{"date":"2023-09-08","current":-18.727692,"twenty":-145.219114,"median":-7.574672,"eighty":45.122099,"marketCap":5787512279},{"date":"2023-09-15","current":-20.239635,"twenty":-145.219114,"median":-7.574672,"eighty":45.122099,"marketCap":6254755717},{"date":"2023-09-22","current":-19.701643,"twenty":-144.797122,"median":-7.574672,"eighty":45.122099,"marketCap":6088497315},{"date":"2023-09-29","current":-21.454756,"twenty":-143.400598,"median":-7.574672,"eighty":45.122099,"marketCap":6630270382},{"date":"2023-10-06","current":-21.728389,"twenty":-143.032342,"median":-7.574672,"eighty":45.122099,"marketCap":6714832844},{"date":"2023-10-13","current":-21.38055,"twenty":-143.032342,"median":-7.574672,"eighty":45.122099,"marketCap":6607338188},{"date":"2023-10-20","current":-21.593891,"twenty":-143.032342,"median":-7.574672,"eighty":45.122099,"marketCap":6673268244},{"date":"2023-10-27","current":-21.16257,"twenty":-143.300049,"median":-7.55957,"eighty":45.146419,"marketCap":6539974871},{"date":"2023-11-03","current":-15.297336,"twenty":-140.032184,"median":-7.55957,"eighty":45.146419,"marketCap":6267655075},{"date":"2023-11-10","current":-16.577399,"twenty":-22.395314,"median":-7.55957,"eighty":45.146419,"marketCap":6787665949},{"date":"2023-11-17","current":-17.008391,"twenty":-21.672735,"median":-7.55957,"eighty":45.146419,"marketCap":6964136656},{"date":"2023-11-24","current":-17.460406,"twenty":-21.484438,"median":-7.55957,"eighty":45.146419,"marketCap":7149215689},{"date":"2023-12-01","current":-17.334262,"twenty":-21.2275,"median":-7.55957,"eighty":45.146419,"marketCap":7097565726},{"date":"2023-12-08","current":-17.334262,"twenty":-20.411236,"median":-7.572349,"eighty":45.140651,"marketCap":7097565726},{"date":"2023-12-15","current":-17.456902,"twenty":-20.127399,"median":-7.572349,"eighty":45.140651,"marketCap":7147780968},{"date":"2023-12-22","current":-17.208119,"twenty":-19.907658,"median":-7.572349,"eighty":45.140651,"marketCap":7045915764},{"date":"2023-12-29","current":-17.695174,"twenty":-19.76602,"median":-7.55957,"eighty":45.146419,"marketCap":7245342009},{"date":"2024-01-05","current":-18.038565,"twenty":-19.665059,"median":-7.54679,"eighty":45.152187,"marketCap":7385944686},{"date":"2024-01-12","current":-18.763892,"twenty":-19.458602,"median":-7.54679,"eighty":45.152187,"marketCap":7682931972},{"date":"2024-01-19","current":-17.747734,"twenty":-19.2678,"median":-7.544467,"eighty":45.157955,"marketCap":7266862827},{"date":"2024-01-26","current":-18.073605,"twenty":-19.134896,"median":-7.54679,"eighty":45.152187,"marketCap":7400291898},{"date":"2024-02-02","current":-17.859862,"twenty":-19.007278,"median":-7.54679,"eighty":45.152187,"marketCap":7312773905},{"date":"2024-02-09","current":-17.512966,"twenty":-18.941814,"median":-7.54679,"eighty":45.152187,"marketCap":7170736507},{"date":"2024-02-16","current":-15.866089,"twenty":-18.881956,"median":-7.54679,"eighty":45.152187,"marketCap":6496417548},{"date":"2024-02-23","current":-17.500434,"twenty":-18.811317,"median":-7.54679,"eighty":45.152187,"marketCap":6410164032},{"date":"2024-03-01","current":-17.989873,"twenty":-18.791838,"median":-7.578157,"eighty":45.146419,"marketCap":6589438742},{"date":"2024-03-08","current":-17.774998,"twenty":-18.791838,"median":-7.603716,"eighty":45.146419,"marketCap":6510732771},{"date":"2024-03-15","current":-16.784182,"twenty":-18.791838,"median":-7.673842,"eighty":45.146419,"marketCap":6147810797},{"date":"2024-03-22","current":-17.010995,"twenty":-18.791838,"median":-7.777023,"eighty":45.146419,"marketCap":6230889321},{"date":"2024-03-28","current":-17.771018,"twenty":-18.791838,"median":-7.81825,"eighty":45.146419,"marketCap":6509275254},{"date":"2024-04-05","current":-17.042828,"twenty":-18.796083,"median":-7.904612,"eighty":45.152187,"marketCap":6242549465},{"date":"2024-04-12","current":-16.911516,"twenty":-18.796083,"median":-8.182691,"eighty":45.152187,"marketCap":6194451372},{"date":"2024-04-19","current":-16.239034,"twenty":-18.796083,"median":-8.560117,"eighty":45.152187,"marketCap":5948130835},{"date":"2024-04-26","current":-16.659633,"twenty":-18.791838,"median":-8.646128,"eighty":45.146419,"marketCap":6102190447},{"date":"2024-05-03","current":-17.157352,"twenty":-18.791838,"median":-8.845112,"eighty":45.146419,"marketCap":6284497762},{"date":"2024-05-10","current":-14.961134,"twenty":-18.791838,"median":-9.293144,"eighty":45.146419,"marketCap":5756535778},{"date":"2024-05-17","current":-14.25989,"twenty":-18.791838,"median":-9.334225,"eighty":45.146419,"marketCap":5486720952},{"date":"2024-05-24","current":-14.40393,"twenty":-18.791838,"median":-9.552464,"eighty":45.146419,"marketCap":5542142376},{"date":"2024-05-31","current":-13.854306,"twenty":-18.791838,"median":-9.739892,"eighty":45.146419,"marketCap":5330665890},{"date":"2024-06-07","current":-15.112755,"twenty":-18.791838,"median":-9.90935,"eighty":45.146419,"marketCap":5814874119},{"date":"2024-06-14","current":-15.586568,"twenty":-18.796083,"median":-9.987659,"eighty":45.152187,"marketCap":5997181434},{"date":"2024-06-21","current":-15.469062,"twenty":-18.800329,"median":-10.068299,"eighty":45.157955,"marketCap":5951969220},{"date":"2024-06-28","current":-17.902568,"twenty":-18.809069,"median":-10.099656,"eighty":45.171414,"marketCap":6888299589},{"date":"2024-07-05","current":-17.284716,"twenty":-18.809069,"median":-10.146845,"eighty":45.171414,"marketCap":6650570851},{"date":"2024-07-12","current":-17.932892,"twenty":-18.809069,"median":-10.187925,"eighty":45.171414,"marketCap":6899967258},{"date":"2024-07-15","current":-18.194437,"twenty":-18.809069,"median":-10.208466,"eighty":45.171414,"marketCap":7000600896},{"date":"2024-08-02","current":-20.490271,"twenty":-18.868176,"median":-10.389456,"eighty":45.307924,"marketCap":7484809124},{"date":"2024-08-09","current":-18.992918,"twenty":-18.884076,"median":-10.451704,"eighty":45.307924,"marketCap":6946488933},{"date":"2024-08-16","current":-18.655115,"twenty":-18.884076,"median":-10.488762,"eighty":45.307924,"marketCap":6822940561},{"date":"2024-08-23","current":-19.004911,"twenty":-18.92096,"median":-10.554325,"eighty":45.307924,"marketCap":6950875266},{"date":"2024-08-30","current":-19.948361,"twenty":-18.942377,"median":-10.636992,"eighty":45.307924,"marketCap":7295933440},{"date":"2024-09-06","current":-19.248769,"twenty":-18.979477,"median":-10.675476,"eighty":45.307924,"marketCap":7040064031},{"date":"2024-09-13","current":-17.667381,"twenty":-18.992918,"median":-10.762419,"eighty":45.307924,"marketCap":6461685590},{"date":"2024-09-20","current":-18.408188,"twenty":-18.992918,"median":-10.826557,"eighty":45.307924,"marketCap":6732629014},{"date":"2024-09-27","current":-17.701837,"twenty":-18.992918,"median":-11.068858,"eighty":45.307924,"marketCap":6474287610},{"date":"2024-10-04","current":-16.284829,"twenty":-18.992918,"median":-11.242743,"eighty":45.307924,"marketCap":5956029551},{"date":"2024-10-11","current":-16.345127,"twenty":-18.992918,"median":-12.040191,"eighty":45.307924,"marketCap":5978083085},{"date":"2024-10-18","current":-16.577706,"twenty":-18.992918,"median":-13.03948,"eighty":45.307924,"marketCap":6063146718},{"date":"2024-10-25","current":-16.698302,"twenty":-18.992918,"median":-13.446915,"eighty":45.307924,"marketCap":6107253787},{"date":"2024-10-31","current":-16.909346,"twenty":-18.992918,"median":-13.562755,"eighty":45.307924,"marketCap":6184441157},{"date":"2024-11-08","current":-16.902216,"twenty":-18.995317,"median":-13.748329,"eighty":45.31946,"marketCap":6072729658},{"date":"2024-11-15","current":-16.383322,"twenty":-18.995317,"median":-13.840323,"eighty":45.31946,"marketCap":5878515995},{"date":"2024-11-22","current":-14.935534,"twenty":-18.995317,"median":-14.176174,"eighty":45.31946,"marketCap":5359033920},{"date":"2024-11-29","current":-15.723236,"twenty":-18.995317,"median":-14.25989,"eighty":45.31946,"marketCap":5641670064},{"date":"2024-12-06","current":-16.172094,"twenty":-18.995317,"median":-14.506273,"eighty":45.31946,"marketCap":5802725297},{"date":"2024-12-13","current":-16.286509,"twenty":-18.995317,"median":-14.813304,"eighty":45.31946,"marketCap":5843778591},{"date":"2024-12-20","current":-15.661628,"twenty":-18.995317,"median":-14.935534,"eighty":45.31946,"marketCap":5619564444},{"date":"2024-12-27","current":-15.98727,"twenty":-18.995317,"median":-15.08243,"eighty":45.31946,"marketCap":5736408436},{"date":"2025-01-03","current":-15.265577,"twenty":-18.995317,"median":-15.112755,"eighty":45.31946,"marketCap":5477456886},{"date":"2025-01-10","current":-15.005943,"twenty":-18.997715,"median":-15.244128,"eighty":45.330996,"marketCap":5384297486},{"date":"2025-01-17","current":-14.205039,"twenty":-18.997715,"median":-15.281457,"eighty":45.330996,"marketCap":5096924424},{"date":"2025-01-24","current":-15.164364,"twenty":-18.997715,"median":-15.281457,"eighty":45.330996,"marketCap":5441140510},{"date":"2025-01-31","current":-14.662699,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":5261137602},{"date":"2025-02-07","current":-14.359059,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":5152188474},{"date":"2025-02-14","current":-13.35573,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":4792182660},{"date":"2025-02-21","current":-11.446164,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":5196558396},{"date":"2025-02-28","current":-10.979464,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":4983545602},{"date":"2025-03-07","current":-12.044139,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5466798509},{"date":"2025-03-14","current":-11.522308,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5229940998},{"date":"2025-03-21","current":-11.46277,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5202916987},{"date":"2025-03-28","current":-11.109046,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5042362567},{"date":"2025-04-04","current":-9.988335,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":4533675297},{"date":"2025-04-11","current":-9.354433,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":4245949060},{"date":"2025-04-17","current":-9.928797,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":4506651286},{"date":"2025-04-25","current":-10.356068,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":4700588308},{"date":"2025-05-02","current":-11.018739,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5046935029},{"date":"2025-05-09","current":-11.380123,"twenty":-19.000114,"median":-15.297336,"eighty":45.26178,"marketCap":5212460492},{"date":"2025-05-16","current":-11.463519,"twenty":-19.000114,"median":-15.297336,"eighty":45.175259,"marketCap":5250658676},{"date":"2025-05-23","current":-11.55734,"twenty":-19.000114,"median":-15.297336,"eighty":45.175259,"marketCap":5293631632},{"date":"2025-05-30","current":-11.626837,"twenty":-19.000114,"median":-15.297336,"eighty":45.007986,"marketCap":5325463452},{"date":"2025-06-06","current":-12.24536,"twenty":-19.000114,"median":-15.297336,"eighty":44.117786,"marketCap":5608766648},{"date":"2025-06-13","current":-12.377404,"twenty":-19.000114,"median":-15.297336,"eighty":-6.098308,"marketCap":5669247106},{"date":"2025-06-20","current":-12.860408,"twenty":-19.002512,"median":-15.301886,"eighty":-6.769341,"marketCap":5890478253},{"date":"2025-06-27","current":-13.82294,"twenty":-19.002512,"median":-15.301886,"eighty":-6.989146,"marketCap":6331348958},{"date":"2025-07-03","current":-14.941841,"twenty":-19.002512,"median":-15.301886,"eighty":-7.017492,"marketCap":6843841257},{"date":"2025-07-11","current":-14.7264,"twenty":-19.002512,"median":-15.301886,"eighty":-7.061175,"marketCap":6745162615},{"date":"2025-07-18","current":-14.653429,"twenty":-19.002512,"median":-15.301886,"eighty":-7.105786,"marketCap":6711739204},{"date":"2025-07-25","current":-14.646479,"twenty":-19.002512,"median":-15.301886,"eighty":-7.221033,"marketCap":6708556022},{"date":"2025-08-01","current":-25.541485,"twenty":-19.026904,"median":-15.342587,"eighty":-7.288415,"marketCap":6850635022},{"date":"2025-08-08","current":-24.394555,"twenty":-19.059439,"median":-15.406519,"eighty":-7.31955,"marketCap":6543009950},{"date":"2025-08-15","current":-25.464231,"twenty":-19.208439,"median":-15.476942,"eighty":-7.439444,"marketCap":6829914162},{"date":"2025-08-22","current":-25.693023,"twenty":-19.327123,"median":-15.573133,"eighty":-7.500784,"marketCap":6891279785},{"date":"2025-08-29","current":-25.32755,"twenty":-19.462842,"median":-15.656683,"eighty":-7.572814,"marketCap":6793254179},{"date":"2025-09-05","current":-35.269594,"twenty":-19.610183,"median":-15.723236,"eighty":-7.595584,"marketCap":9459869441},{"date":"2025-09-12","current":-38.056694,"twenty":-19.731561,"median":-15.763036,"eighty":-7.642541,"marketCap":10207414305},{"date":"2025-09-19","current":-36.689886,"twenty":-19.905803,"median":-15.876073,"eighty":-7.741966,"marketCap":9840814478},{"date":"2025-09-26","current":-37.420831,"twenty":-20.021346,"median":-16.03996,"eighty":-7.801291,"marketCap":10036865690},{"date":"2025-10-03","current":-40.647687,"twenty":-20.250766,"median":-16.203648,"eighty":-7.855354,"marketCap":10902360063},{"date":"2025-10-10","current":-41.758962,"twenty":-20.936243,"median":-16.267488,"eighty":-8.057965,"marketCap":11200421661},{"date":"2025-10-17","current":-43.422902,"twenty":-21.44548,"median":-16.302057,"eighty":-8.466659,"marketCap":11646717103},{"date":"2025-10-24","current":-42.489907,"twenty":-21.627284,"median":-16.365719,"eighty":-8.619683,"marketCap":11396472873},{"date":"2025-10-31","current":-46.865674,"twenty":-22.311833,"median":-16.491552,"eighty":-8.824572,"marketCap":12013640728},{"date":"2025-11-07","current":-46.821444,"twenty":-24.565703,"median":-16.551864,"eighty":-9.220997,"marketCap":12002302521},{"date":"2025-11-14","current":-44.129685,"twenty":-25.310911,"median":-16.577552,"eighty":-9.310347,"marketCap":11312291607},{"date":"2025-11-21","current":-46.202213,"twenty":-25.459477,"median":-16.623152,"eighty":-9.406991,"marketCap":11843567616},{"date":"2025-11-28","current":-52.274467,"twenty":-25.606854,"median":-16.659586,"eighty":-9.54788,"marketCap":13400141532},{"date":"2025-12-05","current":-51.693149,"twenty":-25.977676,"median":-16.714478,"eighty":-9.709339,"marketCap":13251125091},{"date":"2025-12-12","current":-50.00606,"twenty":-36.254884,"median":-16.738094,"eighty":-9.817591,"marketCap":12818653462},{"date":"2025-12-19","current":-49.051939,"twenty":-36.458718,"median":-16.773398,"eighty":-9.930898,"marketCap":12574072128},{"date":"2025-12-26","current":-50.960181,"twenty":-37.51116,"median":-16.804783,"eighty":-9.964551,"marketCap":13063234795},{"date":"2026-01-02","current":-49.987104,"twenty":-38.080464,"median":-16.872737,"eighty":-9.994875,"marketCap":12813794230},{"date":"2026-01-09","current":-51.522544,"twenty":-40.33867,"median":-16.913584,"eighty":-10.055281,"marketCap":13207392005},{"date":"2026-01-16","current":-48.786554,"twenty":-41.579494,"median":-16.936559,"eighty":-10.101905,"marketCap":12506042883},{"date":"2026-01-23","current":-51.680511,"twenty":-42.352038,"median":-16.969214,"eighty":-10.147872,"marketCap":13247885603},{"date":"2026-01-30","current":-53.001116,"twenty":-43.304049,"median":-17.016336,"eighty":-10.177655,"marketCap":13586412084},{"date":"2026-02-06","current":-52.748369,"twenty":-43.896106,"median":-17.042828,"eighty":-10.276361,"marketCap":13521622327},{"date":"2026-02-13","current":-51.674193,"twenty":-45.89007,"median":-17.08842,"eighty":-10.365331,"marketCap":13246265859},{"date":"2026-02-20","current":-52.536693,"twenty":-46.437268,"median":-17.113581,"eighty":-10.415699,"marketCap":13467360905},{"date":"2026-02-27","current":-34.265449,"twenty":-46.808807,"median":-17.154283,"eighty":-10.419492,"marketCap":13055136075},{"date":"2026-03-06","current":-32.554417,"twenty":-46.808807,"median":-17.180856,"eighty":-10.419492,"marketCap":12415831546},{"date":"2026-03-13","current":-31.332977,"twenty":-46.808807,"median":-17.209871,"eighty":-10.419492,"marketCap":11949990075},{"date":"2026-03-20","current":-30.891179,"twenty":-46.808807,"median":-17.218631,"eighty":-10.419492,"marketCap":11781494224},{"date":"2026-03-27","current":-32.155933,"twenty":-46.808807,"median":-17.24834,"eighty":-10.419492,"marketCap":12263854896},{"date":"2026-04-02","current":-32.541423,"twenty":-46.808807,"median":-17.287579,"eighty":-10.419492,"marketCap":12410875786},{"date":"2026-04-10","current":-33.104499,"twenty":-46.808807,"median":-17.33251,"eighty":-10.419492,"marketCap":12625625400},{"date":"2026-04-17","current":-32.597731,"twenty":-46.808807,"median":-17.370954,"eighty":-10.419492,"marketCap":12432350747},{"date":"2026-04-24","current":-32.090963,"twenty":-46.808807,"median":-17.417852,"eighty":-10.419492,"marketCap":12239076094},{"date":"2026-05-01","current":-37.78562,"twenty":-46.808807,"median":-17.460406,"eighty":-10.419492,"marketCap":12355028686},{"date":"2026-05-08","current":-38.422456,"twenty":-46.808807,"median":-17.499692,"eighty":-10.425443,"marketCap":12563259507},{"date":"2026-05-15","current":-38.250612,"twenty":-46.808807,"median":-17.54086,"eighty":-10.441583,"marketCap":12507070238},{"date":"2026-05-22","current":-38.301154,"twenty":-46.808807,"median":-17.626193,"eighty":-10.45769,"marketCap":12523596493},{"date":"2026-05-29","current":-39.084564,"twenty":-46.821444,"median":-17.65446,"eighty":-10.515842,"marketCap":12779753455},{"date":"2026-06-05","current":-37.972628,"twenty":-46.808807,"median":-17.690774,"eighty":-10.584827,"marketCap":12416175832},{"date":"2026-06-12","current":-37.31052,"twenty":-46.808807,"median":-17.738974,"eighty":-10.668419,"marketCap":12199681883},{"date":"2026-06-18","current":-37.558179,"twenty":-46.808807,"median":-17.769888,"eighty":-10.69486,"marketCap":12280660536},{"date":"2026-06-26","current":-39.595044,"twenty":-46.821444,"median":-17.818766,"eighty":-10.726786,"marketCap":12946668637},{"date":"2026-07-02","current":-40.024656,"twenty":-46.821444,"median":-17.854581,"eighty":-10.726786,"marketCap":13087141809},{"date":"2026-07-10","current":-32.483705,"twenty":-46.821444,"median":-17.871767,"eighty":-10.726786,"marketCap":10621424474},{"date":"2026-07-17","current":-27.621511,"twenty":-46.821444,"median":-17.880886,"eighty":-10.979464,"marketCap":9031598685},{"date":"2026-07-24","current":-28.23813,"twenty":-46.821444,"median":-17.925673,"eighty":-11.109046,"marketCap":9233219003},{"date":"2026-07-31","current":-15.666504,"twenty":-46.83029,"median":-17.93492,"eighty":-11.257113,"marketCap":8854300676},{"date":"2026-08-07","current":-16.022293,"twenty":-46.83029,"median":-17.93492,"eighty":-11.326236,"marketCap":9055383705},{"date":"2026-08-14","current":-16.42807,"twenty":-46.83029,"median":-17.93492,"eighty":-11.457268,"marketCap":9284718070},{"date":"2026-08-21","current":-17.277849,"twenty":-46.83029,"median":-17.93492,"eighty":-11.52511,"marketCap":9764990760},{"date":"2026-08-28","current":-18.356979,"twenty":-46.83029,"median":-17.973741,"eighty":-11.565738,"marketCap":10374887222},{"date":"2026-09-04","current":-17.092603,"twenty":-46.83029,"median":-17.982683,"eighty":-11.643516,"marketCap":9660294637},{"date":"2026-09-11","current":-16.363381,"twenty":-46.83029,"median":-17.982683,"eighty":-11.688179,"marketCap":9248157519},{"date":"2026-09-15","current":-15.125468,"twenty":-46.83029,"median":-17.982683,"eighty":-11.712128,"marketCap":8548521523}],"updateTime":1789625063101},"$inf$@#url:\"https://stock-news.skytigris.cn/v2/news/list\",params:#symbols:\"IONS\",pageSize:20,pageCount:7,lang_content:\"en\",edition:\"fundamental\",,,undefined,":[{"items":[{"id":"1193085095","title":"Movement Alert｜Ionis Pharmaceuticals Falls 20.03% in Regular Trading, Core Pipeline Drug Eplontersen Fails Phase 3 Cardiac Trial Primary Endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=1193085095","media":"Market Focus","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1193085095?lang=en_us&edition=fundamental","pubTime":"2026-07-09 22:47","pubTimestamp":1783608425,"startTime":"0","endTime":"0","summary":"On July 9, Ionis Pharmaceuticals fell 20.03% in regular trading, trading at $67.55/share, with turnover of $538 million. The sharp decline was triggered by the announcement that its drug Eplontersen...","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650209659","title":"Ionis Pharmaceuticals (IONS) Stock Slammed by Phase 3 Trial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2650209659","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650209659?lang=en_us&edition=fundamental","pubTime":"2026-07-09 22:07","pubTimestamp":1783606054,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals stock fell hard on Thursday due to a clinical trial failure.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ionis-pharmaceuticals-ions-stock-slammed-by-phase-3-trial-results?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ionis-pharmaceuticals-ions-stock-slammed-by-phase-3-trial-results?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650927783","title":"Ionis Pharmaceuticals falls -17.6%","url":"https://stock-news.laohu8.com/highlight/detail?id=2650927783","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650927783?lang=en_us&edition=fundamental","pubTime":"2026-07-09 22:00","pubTimestamp":1783605613,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals (IONS) is down -17.6%, or -$14.84 to $69.62. Published first on TheFly – the ultimate source for real-time, market-moving bre...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ionis-pharmaceuticals-falls-17-6-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ionis-pharmaceuticals-falls-17-6-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650922509","title":"Exchange-Traded Funds Higher, Equity Futures Mixed Pre-Bell Thursday as Chip Stocks Rebound Despite US-Iran Tensions","url":"https://stock-news.laohu8.com/highlight/detail?id=2650922509","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650922509?lang=en_us&edition=fundamental","pubTime":"2026-07-09 21:12","pubTimestamp":1783602739,"startTime":"0","endTime":"0","summary":"The broad market exchange-traded fund SPDR S&P 500 ETF Trust (SPY) was up 0.3%, and the actively traded Invesco QQQ Trust (QQQ) advanced 0.9% in Thursday's premarket activity, as investors returned to","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["QQQ","FAS","IVV","IONS","EQR","IWM","XLY","AMAT","VIS","IGV","IYW","SPY.AU","VHT.AU","XLE","FCEL","BITO","SRE","FDN","USO","IYK","BETH","XLF","RTH.AU","SLV","RTH","SPY","XLP","XLI","GLD","EEM","IYH","XLV","XSD","XRT","IGM","VHT","BR","IBB","AZN","SOXX",".IXIC","EXI","IYJ","XLK","UNG","EETH","IYE","LEVI","FAZ","VDC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650592490","title":"Astrazeneca and Ionis Stocks Sink on Trial Miss and Analysts See an Overreaction","url":"https://stock-news.laohu8.com/highlight/detail?id=2650592490","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650592490?lang=en_us&edition=fundamental","pubTime":"2026-07-09 20:45","pubTimestamp":1783601100,"startTime":"0","endTime":"0","summary":"AstraZeneca shares slumped after the British-Swedish drugmaker announced a late-stage trial failure, denting the commercial prospects for its gene silencing drug. Analysts were seeing an overreaction.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2237443978.SGD","LU2237443549.SGD","LU2417539215.USD","BK4585","LU1267930573.SGD","BK4139","LU0289739699.SGD","LU0058720904.USD","LU2237443895.HKD","LU2462157665.USD","LU0320765992.SGD","IE00B3T34201.USD","LU0128525929.USD","LU0029864427.USD","LU0889565916.HKD","LU0432979614.USD","LU2468319806.SGD","LU2237443622.USD","LU0310800379.SGD","LU2089984988.USD","LU2237443465.HKD","LU0109394709.USD","LU2237443382.USD","BK4588","LU1829250122.USD","BK4568","LU0708994859.HKD","AZN","LU2456880835.USD","IONS","LU2236285917.USD","AZNH","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650921640","title":"Ionis Pharmaceuticals Shares Sink After Late-stage Trial Failed to Meet Primary Goal","url":"https://stock-news.laohu8.com/highlight/detail?id=2650921640","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650921640?lang=en_us&edition=fundamental","pubTime":"2026-07-09 20:04","pubTimestamp":1783598640,"startTime":"0","endTime":"0","summary":"Shares of Ionis Pharmaceuticals tumbled after the company said a late-stage trial of its drug for a rare type of heart disease failed to meet its primary efficacy endpoint.The stock sank 23%, to $65.1","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0058720904.USD","LU2237443549.SGD","LU0320765992.SGD","LU1267930573.SGD","LU0109394709.USD","LU2236285917.USD","LU2462157665.USD","BK4585","LU2456880835.USD","LU2237443978.SGD","AZN","LU0889565916.HKD","LU2237443465.HKD","LU0708994859.HKD","IE00B3T34201.USD","LU2468319806.SGD","LU2237443895.HKD","LU1829250122.USD","BK4007","IONS","LU0128525929.USD","BK4568","AZNH","LU2237443622.USD","BK4139","LU0310800379.SGD","LU0432979614.USD","LU2417539215.USD","LU2237443382.USD","LU0289739699.SGD","LU2089984988.USD","BK4588","LU0029864427.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650295609","title":"U.S. Stocks on the Move-levi, Ionis Pharmaceuticals, Gloo Holdings","url":"https://stock-news.laohu8.com/highlight/detail?id=2650295609","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650295609?lang=en_us&edition=fundamental","pubTime":"2026-07-09 19:37","pubTimestamp":1783597031,"startTime":"0","endTime":"0","summary":"BUZZ-U.S. STOCKS ON THE MOVE-Levi, Ionis Pharmaceuticals, Gloo HoldingsWorkspace search string for individual stock moves:STXBZThe Day Ahead newsletter: https://refini.tv/3LI4BU7The Morning News Call ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260709:nL6N43B0NZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["FCXG","GLSI","SETM","IONS","03165","COPP","COPA","LU2362541513.USD","FCX","LU1267930813.SGD","LU1162221912.USD","ICLR","EART","GLOO","ICOP","EKG","LU1244550494.USD","LU0630314457.HKD","BHP.AU","LU1880407215.USD","LU0757428866.USD","GMET","LU2237443895.HKD","LU0130102774.USD","LU0266512473.USD","LU2091194634.USD","SCCO","LU0648001328.SGD","LEVI","IQV","FTXG","LU1894683348.USD","LU1989764664.SGD","LU2237443549.SGD","IE00B2B36J28.USD","FTRE","LU0390134368.USD","IE00B7SZLL34.SGD","LU1051770623.HKD","PICK","LU1487256676.USD","BK4139","HEAL","AZN.UK","COPX","PEP","LU1153584641.USD","LU0788109048.HKD","CRL","LU1989772923.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650592980","title":"S&P 500 Futures Climb in Premarket Trading; Alnylam Pharmaceuticals, Bridgebio Pharma Lead","url":"https://stock-news.laohu8.com/highlight/detail?id=2650592980","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650592980?lang=en_us&edition=fundamental","pubTime":"2026-07-09 19:30","pubTimestamp":1783596600,"startTime":"0","endTime":"0","summary":"This article was automatically generated by Barrons.com using technology from Automated Insights.With U.S. stock markets set to open in two hours, Alnylam Pharmaceuticals Inc. (ALNY) was up 18.4% in p","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["VYM","KLIC","CFO","FLAO","PTLC","SSO","BBIO","AEIS","GBXB","PTL","SPYM","FELC","ALNY","FLCC","SH","LGH","UXJA","XUSP","CDP","SFY","CGUS","PBE","XPAY","FEBT","SPY","OALC","OEX","TSPA","VOO","CBRS","UOCT","SCHG","MRCP","HELO","GPIX","SPMO","PBJL","ACLC","CPST","BKLC","DBB","IONS","GSUS","SPHD","VOOG",".SPX","VUG","ISSXF","SPUS","ALLW"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650926989","title":"Schwab Strategists Warn of a Major Market Shift: the Era of Easy Index Gains is Officially Over.","url":"https://stock-news.laohu8.com/highlight/detail?id=2650926989","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650926989?lang=en_us&edition=fundamental","pubTime":"2026-07-09 19:09","pubTimestamp":1783595340,"startTime":"0","endTime":"0","summary":"The 'great moderation' is over. Welcome to the temperamental era of investing, strategists say.Charles Schwab strategists Liz Ann Sonders and Kevin Gordon say we've entered the \"temperamental era.\"Inv","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CGUI","PSC","FLV","CGUS","MDLV","IUS","ILCV","DIVZ","MAPP","FT","SCHW","US12M.BOND","EQRR","VTV","CGDV","XOEX","CDC","AZN","REGL","RHTX","PEP","US10Y.BOND","US5Y.BOND","RULE","SAMT","DFUV","RMIF","BAMA","DECU","FXD","ADPV","LCG","MODL","LGH","US2Y.BOND","IMCG","VXZ","CLIX","BSR","TEQI","US30Y.BOND","SDOG","VOTE","EES","IONS","PRVS","ARP","BKDV","LEVI","HIDV"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650928280","title":"Major Drugmaker Loses $27 Billion in Market Value After Failed Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2650928280","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650928280?lang=en_us&edition=fundamental","pubTime":"2026-07-09 17:53","pubTimestamp":1783590780,"startTime":"0","endTime":"0","summary":"Shares in AstraZeneca and Ionis decline on heart drug trial failureAstraZeneca's stock fell about 8% in London.Shares in AstraZeneca and Ionis Pharmaceuticals slid on Thursday after the companies anno","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2236285917.USD","LU0128525929.USD","LU2417539215.USD","LU2089984988.USD","LU0320765992.SGD","IE00B3T34201.USD","BK4568","LU2237443978.SGD","LU0289739699.SGD","AZNH","LU0310800379.SGD","LU1829250122.USD","IONS","BK4007","LU0432979614.USD","LU0708994859.HKD","LU1267930573.SGD","LU2456880835.USD","LU0058720904.USD","LU2237443382.USD","LU2237443465.HKD","LU0889565916.HKD","BK4588","LU2468319806.SGD","LU2237443549.SGD","LU2237443622.USD","LU0029864427.USD","BK4139","BK4585","LU2237443895.HKD","LU2462157665.USD","LU0109394709.USD","AZN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650194016","title":"AstraZeneca says CARDIO-TTRansform trial did not meet primary efficacy endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2650194016","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650194016?lang=en_us&edition=fundamental","pubTime":"2026-07-09 17:15","pubTimestamp":1783588532,"startTime":"0","endTime":"0","summary":"The CARDIO-TTRansform Phase III trial for AstraZeneca (AZN) and Ionis’ (IONS) Wainua in patients with transthyretin-mediated amyloid cardiomyopathy...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/astrazeneca-says-cardio-ttransform-trial-did-not-meet-primary-efficacy-endpoint-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/astrazeneca-says-cardio-ttransform-trial-did-not-meet-primary-efficacy-endpoint-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU2237443549.SGD","BK4585","LU2468319806.SGD","LU0289739699.SGD","LU2462157665.USD","LU2237443382.USD","AZNH","LU2089984988.USD","LU0029864427.USD","LU2237443895.HKD","LU1829250122.USD","BK4568","LU2236285917.USD","LU1267930573.SGD","LU0109394709.USD","LU2237443622.USD","LU0708994859.HKD","BK4007","LU2417539215.USD","LU0310800379.SGD","IONS","LU0320765992.SGD","AZN","BK4588","LU0889565916.HKD","LU2237443465.HKD","BK4139","LU2237443978.SGD","LU0058720904.USD","LU2456880835.USD","LU0128525929.USD","LU0432979614.USD","IE00B3T34201.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650942089","title":"Tech Rebound Lifts European Shares After Three-day Slide","url":"https://stock-news.laohu8.com/highlight/detail?id=2650942089","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650942089?lang=en_us&edition=fundamental","pubTime":"2026-07-09 16:32","pubTimestamp":1783585956,"startTime":"0","endTime":"0","summary":"Tech rebound lifts European shares after three-day slideTech stocks gain, healthcare lagsAstraZeneca slumps after late-stage trial setbackSpanish shares rebound after tensions with US easeUpdates afte","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260709:nL6N43B0F9:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["DIPS","CLSE","ARTY","SOXX","NVDW","FTEC","NVDU","TYLG","TTEQ","VGT","WISE","NVDX","AZN.UK","SOXY","ROM","SHOC","NVDA","NVII","USXF","NVDY","VT","03165","SNPE","NVD2.UK","NVDS","XLK","CHAT","IETC","SOXQ","AIFD","NVIW.SI","ILDR","SMHX","2NVD.UK","AIPI","ESUM","3NVD.UK","USD","ANV","IONS","NVDL","CNEQ","SPTE","NVDQ","AGOX","EFIV","CCC.UK","NVDS.UK","NVD3.UK","SMH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650485942","title":"Ionis Pharmaceuticals Shares Fall 13.8% Premarket After Drug Made in Partnership with Astrazeneca Fails Late-stage Heart Disease Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2650485942","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650485942?lang=en_us&edition=fundamental","pubTime":"2026-07-09 16:28","pubTimestamp":1783585727,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260709:nL4N43B0P5:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LU2125909247.SGD","LU0058720904.USD","IE00BJJMRZ35.SGD","LU1880407215.USD","IE00BJT1NW94.SGD","LU0211326839.USD","LU0557290698.USD","LU1923622614.USD","LU1323610961.USD","LU0211328371.USD","LU0857590862.USD","LU0047473722.EUR","03165","LU0432979614.USD","LU1267930227.SGD","LU0640478417.SGD","LU2108987350.USD","LU1019632923.USD","LU1003076772.USD","LU1989772840.SGD","LU2114397693.USD","LU0029864427.USD","LU0047473722.SGD","IONS","LU0920840948.USD","LU1057294990.SGD","LU0553294199.USD","LU1301847155.USD","LU1814569148.SGD","LU2091194634.USD","LU2293690082.USD","LU2539964713.USD","LU0859254822.USD","LU1061106388.HKD","LU1170363599.USD","LU0757432116.USD","LU0203347892.USD","LU1003077747.HKD","LU1064927863.SGD","LU0011850046.USD","LU1267930490.SGD","AZN.UK","LU1019634622.SGD","LU2237443622.USD","LU1355424745.HKD","LU0310799852.SGD","LU1291159041.SGD","LU2324357040.USD","LU0390134368.USD","LU2237443382.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1163884289","title":"Movement Alert｜Ionis Pharmaceuticals Falls 14.75% in Pre-Market Trading, Phase 3 ATTR-CM Trial for Eplontersen Fails Primary Endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=1163884289","media":"Market Focus","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1163884289?lang=en_us&edition=fundamental","pubTime":"2026-07-09 16:21","pubTimestamp":1783585271,"startTime":"0","endTime":"0","summary":"On July 9, Ionis Pharmaceuticals fell 14.75% in pre-market trading, trading at $74.68/share, with turnover of $86,200. The sharp decline was triggered by the announcement that the Phase 3...","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650417009","title":"Astrazeneca Top Loser on FTSE 100 After Heart Disease Drug Fails Late-stage Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2650417009","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650417009?lang=en_us&edition=fundamental","pubTime":"2026-07-09 15:26","pubTimestamp":1783581966,"startTime":"0","endTime":"0","summary":"BUZZ-AstraZeneca top loser on FTSE 100 after heart disease drug fails late-stage trial** Shares of AstraZenecaAZN.Lslump as much as 9.6% to 12,874p; on track for their worst day since 2017** AZN is to","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260709:nL6N43B0EP:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00B3T34201.USD","LU0823416689.USD","LU0310800379.SGD","LU1196032939.SGD","LU0784383803.USD","LU1267930573.SGD","IONS","AZN.UK","LU0432979614.USD","LU1267930490.SGD","LU0114720955.EUR","LU1496350502.SGD","LU1481600234.SGD","LU0047473722.SGD","LU0545039389.USD","LU1023059063.AUD","IE00BJT1NW94.SGD","LU0792757196.USD","LU1923622614.USD","LU0310800965.SGD","LU0640478417.SGD","LU0708994859.HKD","LU2108987350.USD","LU1153585028.USD","LU0887340254.USD","LU2539964713.USD","LU1051770623.HKD","LU0171276677.USD","LU2112291526.USD","LU0266013472.USD","LU0058720904.USD","LU0077335932.USD","BK5011","BK4139","LU0960981461.USD","LU1003076772.USD","LU0310799852.SGD","LU1829250122.USD","LU2357627491.SGD","LU1084165304.USD","IE00BKPKM643.USD","03165","IE00BJJMRZ35.SGD","LU0289739699.SGD","LU1989772840.SGD","IE00B4R5TH58.HKD","LU1880407215.USD","LU0203345920.USD","IE0034235188.USD","LU1880407132.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650167941","title":"Astrazeneca Shares Set for Their Biggest One-day Fall Since March 2020","url":"https://stock-news.laohu8.com/highlight/detail?id=2650167941","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650167941?lang=en_us&edition=fundamental","pubTime":"2026-07-09 15:16","pubTimestamp":1783581404,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260709:nL8N43B0DD:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LU0920840948.USD","LU1481600234.SGD","IE00B2B36J28.USD","LU0128525689.USD","LU0077335932.USD","LU0211326839.USD","LU0052756011.USD","LU2279689827.SGD","LU1015430645.USD","LU0499090636.EUR","LU2125909247.SGD","LU1023059063.AUD","AZN.UK","LU0211327993.USD","03165","LU0997586432.USD","LU0203345920.USD","LU2089984988.USD","LU1355424745.HKD","LU2237443465.HKD","LU0128525929.USD","LU1061106388.HKD","IONS","LU0957799991.USD","LU0310800965.SGD","LU0964806797.USD","LU1829250122.USD","LU2468319806.SGD","LU1923622614.USD","LU1046234339.USD","LU0823416689.USD","LU2237443549.SGD","LU1880407215.USD","LU1487256676.USD","LU0969580561.USD","LU1496350502.SGD","LU2357627491.SGD","LU0784384876.USD","LU0823399737.USD","LU0887340254.USD","LU1323610961.USD","LU0345777659.USD","LU2237443382.USD","LU0640478417.SGD","LU2133065610.SGD","LU1989772840.SGD","LU2108987350.USD","LU0889565080.SGD","LU0827474353.SGD","LU0047473722.EUR"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650966941","title":"Astrazeneca Shares Down 9% After Late-stage Trial Miss for Nerve Disease Drug Wainua","url":"https://stock-news.laohu8.com/highlight/detail?id=2650966941","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650966941?lang=en_us&edition=fundamental","pubTime":"2026-07-09 15:11","pubTimestamp":1783581087,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260709:nL8N43B0DD:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LU1153585028.USD","LU2108987350.USD","LU1829250122.USD","LU0640478417.SGD","03165","LU0077335932.USD","LU0289739699.SGD","LU0058720904.USD","LU0792757196.USD","LU2357627491.SGD","LU0266013472.USD","LU1023059063.AUD","IE0034235188.USD","LU1051770623.HKD","IONS","IE00BJT1NW94.SGD","LU0823416689.USD","BK4139","LU1496350502.SGD","LU1923622614.USD","LU1989772840.SGD","LU0171276677.USD","LU1196032939.SGD","AZN.UK","LU0545039389.USD","LU1880407132.USD","IE00BJJMRZ35.SGD","LU0310799852.SGD","LU0432979614.USD","LU2539964713.USD","LU2112291526.USD","LU0203345920.USD","LU0708994859.HKD","LU1267930573.SGD","IE00B3T34201.USD","LU0047473722.SGD","BK5011","LU1481600234.SGD","LU1880407215.USD","LU0114720955.EUR","IE00BKPKM643.USD","LU0960981461.USD","LU0887340254.USD","LU1084165304.USD","LU1267930490.SGD","IE00B4R5TH58.HKD","LU0784383803.USD","LU0310800965.SGD","LU0310800379.SGD","LU1003076772.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650941212","title":"European Shares Gain as Tech Stocks Rebound; Middle East in Focus","url":"https://stock-news.laohu8.com/highlight/detail?id=2650941212","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650941212?lang=en_us&edition=fundamental","pubTime":"2026-07-09 15:03","pubTimestamp":1783580580,"startTime":"0","endTime":"0","summary":"European shares gain as tech stocks rebound; Middle East in focusFor a Reuters live blog on U.S., UK and European stock markets, clickLIVE/or type LIVE/ in a news windowJuly 9 (Reuters)-European share","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260709:nL6N43B0DZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SG9999015945.SGD","LU1244550494.USD","IE00BJT1NW94.SGD","LU1551013342.USD","SGXZ81514606.USD","LU0047473722.EUR","BK4532","LU0920783379.SGD","LU1720051108.HKD","LU0823434740.USD","LU0061474960.USD","NVDO","LU2403377893.USD","LU2471134796.USD","LU2360032135.SGD","ROM","LU1316542783.SGD","LU1301847155.USD","LU2065169927.USD","LU0823414478.USD","LU0323240290.USD","SOXX","IE00BJJMRZ35.SGD","LU0976567544.SGD","SG9999017495.SGD","LU0058720904.USD","LU0124676726.USD","LU2357305700.SGD","IE00B19Z9505.USD","LU1989772923.USD","LU2125154935.USD","LU0353189763.USD","LU0957791311.USD","LU0175139822.USD","LU0154236417.USD","LU0323591593.USD","SGXZ23171101.USD","LU0320765059.SGD","VGT","LU0077335932.USD","LU1935042215.USD","LU1066051225.USD","JGRO","IE00BYXW3230.USD","LU1868836914.USD","LU1366333091.USD","LU0997586515.USD","LU2089984988.USD","LU2361044949.HKD","IE00BN29S564.USD","SMH","IE00B19Z8W00.USD","LU1078025761.USD","LU2065171402.SGD","LU0251132253.USD","LU0943347566.SGD","HK0000306701.USD","LU0056508442.USD","IE0009355771.USD","LU1046234339.USD","LU0868494617.USD","LU1153585028.USD","LU0859254822.USD","LU1273509221.SGD","LU0061475181.USD","LU0127658192.USD","LU0203202063.USD","IE0004445015.USD","LU0823434583.USD","LU0128525929.USD","LU2750360997.AUD","SG9999018865.SGD","LU0289739343.SGD","LU0738911758.USD","SG9999014898.SGD","LU0708995401.HKD","IE0003U64NQ7.SGD","ARTY","IE0009G5SDU7.USD","IE00BQXX3C00.GBP","LU1202635105.USD","LU0494093205.USD","METV","SG9999015986.USD","LU1642822529.SGD","NVD3.UK","FAI","LU1037948897.HKD","LU1934455194.USD","LU0215105999.USD","LU0887340254.USD","LU0080751232.USD","LU0029864427.USD","IE00BFTCPJ56.SGD","LU0082616367.USD","LU1267930490.SGD","BK4567","IE00BFSS8Q28.SGD","LU1015430645.USD","HK0000304797.USD","LU2462591350.SGD","LU2191332357.HKD","BK4588","LU1923622291.USD","LU2394011477.USD","VT","LU0107464264.USD","LU0143551892.USD","LU0972486137.USD","LU2092627202.USD","LU2322448957.HKD","LU0310800379.SGD","LU0466842654.USD","TTEQ","IE0002141913.USD","LU2065170008.USD","LU1868836757.USD","LU0234572021.USD","LU1267930573.SGD","LU2430703095.HKD","LU1880407215.USD","LU0784383803.USD","LU1989771016.USD","LU0057025933.USD","HK0000914660.USD","LU2462157665.USD","FDTX","LU1496350171.SGD","LU2047632596.USD","IE00BJJMRY28.SGD","LU1366192091.USD","LU1829250122.USD","LU2089985449.USD","LU0106261372.USD","LU2247934214.USD","LU0942090050.USD","2NVD.UK","LU1116320901.HKD","LU1983299246.USD","LU2413666699.HKD","SNVD.UK","LU2077746001.SGD","IE00B5949003.HKD","LU0109391861.USD","LU0432979614.USD","LU1153584641.USD","IE00B7KXQ091.USD","BK4141","BK4549","LU0171276677.USD","LU0211326755.USD","IE0004445239.USD","SOXY","LU0265550946.USD","LU2023250504.SGD","LU2213496289.HKD","LU0820562030.AUD","LU1355424745.HKD","TYLG","LU0256863811.USD","HK0000320223.HKD","IE00BKPKM643.USD","LU0267386448.USD","LU2237443895.HKD","LU2361044865.SGD","LU2265009873.SGD","LU0138981039.USD","LU1400636657.SGD","LU2896262040.SGD","LU2602419157.SGD","IE00B3S45H60.SGD","LU0342679015.USD","LU1718418525.SGD","SNPE","SG9999015341.SGD","LU0289960550.SGD","SGXZ31699556.SGD","LU0882574055.USD","LU1127390331.HKD","07388","LU2355687059.USD","HK0000304805.HKD","LU2954938101.SGD","LU1633808545.USD","BK5011","IE00BFSS7M15.SGD","LU0345770308.USD","LU1880407132.USD","LU1951200564.SGD","LU0949170772.SGD","LU1066051811.HKD","LU0011850046.USD","LU0708994859.HKD","IE00B3M56506.USD","LU0122379950.USD","BK4614","LU0345769631.USD","LU2756315318.SGD","SOXQ","LU0545039389.USD","LU1057294990.SGD","SG9999014880.SGD","LU1267930730.SGD","LU2326559502.SGD","LU1935043536.SGD","SG9999015952.SGD","ESUM","IE0004086264.USD","SG9999014914.USD","LU2249611893.SGD","LU2083900584.USD","IE00BK4W5M84.HKD","LU0094547139.USD","LU2097344431.USD","LU1261432733.SGD","IETC","IE00BZ1G4Q59.USD","LU0348723411.USD","LU1923623000.USD","NVD2.UK","LU0079474960.USD","SHOC","NVDL","LU0187121727.USD","LU0310799852.SGD","LU1880398471.USD","IE0004091025.USD","LU2125909916.SGD","LU1066053197.SGD","LU0211326839.USD","LU0047473722.SGD","SG9999002224.SGD","SG9999014906.USD","IE00BJLML261.HKD","LU2417539215.USD","LU2487616109.SGD","LU2637965513.SGD","SG9999015978.USD","LU1064927863.SGD","LU0234570918.USD","LU1064131342.USD","LU2264538146.SGD","LU0323239441.USD","LU0526926950.USD","LU1232071149.USD","LU1267930227.SGD","BK4139","LU0661504455.SGD","ILDR","LU2357125470.USD","IE0001KFT4U8.USD","LU0861579265.USD","LU1145028129.USD","IE000W1ABFV2.USD","LU2324357040.USD","LU2100268510.USD","LU0345770993.USD","LU1571399168.USD","ABFL","LU1815333072.USD","LU1861127337.USD","LU2272731600.USD","LU1791710400.SGD","LU2168564149.EUR","LU2473716301.USD","IE00B4YYXB79.USD","LU0354030438.USD","LU0787776722.HKD","LU0289961442.SGD","LU0157215616.USD","LU1839511570.USD","IE00BKPKM429.USD","LU2272731782.SGD","BK4585","SG9999001424.SGD","LU0472753341.HKD","LU2430703251.USD","AIPI","SGXZ57979304.SGD","IE00BQXX3F31.USD","LU0979878070.USD","LU0225283273.USD","LU2756315664.SGD","BK4598","LU0965508806.USD","LU2168564495.EUR","NULC","LU1429558221.USD","LU1670756490.USD","IONS","NVDX","FTEC","BK4587","LU1548497426.USD","LU2413666426.HKD","LU0444973449.USD","LU0345777147.USD","LU1003076772.USD","LU0171293334.USD","LU2114397693.USD","LU0096364046.USD","LU0198837287.USD","LU0170899867.USD","LU1815336760.USD","LU2505996509.AUD","LU1674673691.USD","LU1551013425.SGD","LU0557290698.USD","LU0784385840.USD","LU0786609619.USD","LU0719512351.SGD","LU2237443622.USD","LU2433249047.HKD","LU0792757196.USD","SG9999013999.USD","LU2860962120.EUR","LU0889565080.SGD","LU1066051498.USD","LU2148611432.USD","LU1721428933.USD","LU2294711713.HKD","LU0496365809.HKD","LU1119994496.HKD","CLSE","LU0308772762.SGD","BK4592","LU1196032939.SGD","LU2552382132.HKD","LU0857590862.USD","IE00BHPRN162.USD","LU0345768153.USD","LU1974910355.USD","LU2322448791.USD","LU2461242641.AUD","LU2505996681.GBP","LU0444971666.USD","AIFD","LU0203345920.USD","LU0097036916.USD","LU2471134879.HKD","AZN.UK","LU2244417387.USD","LU1244550577.SGD","LU0960981461.USD","LU0823399737.USD","LU1989764664.SGD","IE00BMPRXR70.SGD","LU1992135399.USD","LU0957799991.USD","LU0965509010.AUD","LU1934455863.HKD","LU0575583348.USD","LU2211815571.USD","LU1935042488.USD","LU2290526834.HKD","LU2491050071.SGD","DIPS","3NVD.UK","LU1861220033.SGD","LU1069344957.HKD","BK4543","IE0005OL40V9.USD","LU2462591277.SGD","LU2242650005.HKD","SGXZ99366536.SGD","IE00BJTD4V19.USD","NVDW","IE00BQXX3D17.EUR","LU0354030511.USD","LU1868837300.USD","LU0964806797.USD","LU1645745479.HKD","LU0081259029.USD","LU0985320562.USD","LU0266013472.USD","LU1267930813.SGD","LU0006306889.USD","NVDA","LU1035775433.USD","IE00BKDWB100.SGD","LU1988902786.USD","LU2746668974.SGD","LU2237443382.USD","LU0788109477.HKD","LU1400636491.USD","LU2168563687.JPY","LU2237443465.HKD","LU0052756011.USD","LU2357627491.SGD","BK4581","BK4529","IE00BDCRKT87.USD","LU0889566641.SGD","LU2999663052.SGD","LU1019632923.USD","SG9999000418.SGD","WISE","IXN","LU0069063385.USD","LU2237438978.USD","LU1487256676.USD","TRFK","NVDQ","LU0128525689.USD","LU0964807845.USD","LU0289739699.SGD","USD","SPTE","NVDB","IE00B775SV38.USD","CNEQ","LU2491050154.USD","NVDS","LU0114720955.EUR","LU1791710582.SGD","HK0000532082.HKD","LU0882574139.USD","USXF","LU1481599808.USD","LU2125909593.SGD","IE0009356076.USD","LU2543165471.USD","NVDD","AGOX","LU1244550221.USD","LU0256863902.USD","LU2272731865.HKD","SGXZ51526630.SGD","LU0823421333.USD","LU2054465674.USD","LU2360106780.USD","IE00B2B36J28.USD","LU0070217475.USD","LU0757432116.USD","LU2089283258.USD","LU1623119135.USD","IE000Q6AESB8.SGD","NVDG","GB00BDT5M118.USD","SMHX","LU0316494557.USD","LU1170363599.USD","IE00BKVL7J92.USD","LU0827474353.SGD","LU2420271590.USD","LU0345768740.USD","LU1814569148.SGD","SG9999014542.SGD","LU1280957306.USD","07788","LU0889565833.HKD","LU2458330243.SGD","LU2237957902.USD","LU2237443978.SGD","IE00BZ199S13.USD","LU1935043023.USD","LU1720051017.SGD","LU0174119429.USD","LU2539964713.USD","BK4554","LU0158827781.USD","LU2092937148.SGD","IE00B3T34201.USD","03165","LU0353189680.USD","LU0683600562.USD","LU2271345857.HKD","BK4550","LU2746668461.USD","LU2242649171.HKD","NVD","LU1084165304.USD","LU1917777945.USD","BK4527","NVYY","NVDY","LU2168564065.EUR","LU2063271972.USD","LU2456880835.USD","LU0276348264.USD","LU1989764748.USD","LU2463028550.USD","LU0963555726.SGD","LU0868494708.USD","LU1400636574.HKD","LU1880398554.USD","LU1699723380.USD","LU2236285917.USD","LU0823421416.USD","LU2111349929.HKD","LU1023059063.AUD","LU0823416689.USD","LU0689472784.USD","LU0724617625.USD","IE00BDRTCR15.USD","HK0000320264.USD","LU2087621335.USD","LU2471134952.CNY","LU0640476718.USD","ANV","BK4605","LU0965509283.SGD","IE00BMPRXN33.USD","LU2592432038.USD","BK4612","LU1674673428.USD","HK0000306685.HKD","LU2458330169.SGD","LU2089284900.SGD","LU2430703178.SGD","LU1868837136.USD","IE00BWXC8680.SGD","LU0265550359.USD","LU0969580561.USD","LU0210536198.USD","LU0997586432.USD","LU1914381329.SGD","BK4548","LU0053666078.USD","SG9999015358.SGD","LU0061474705.USD","BK4533","LU2293690082.USD","LU0238689110.USD","LU1104425308.USD","SG9999001176.USD","IE000ITXATA3.USD","IE000YTNTUN2.SGD","LU2023250330.USD","LFGY","LU0957808578.USD","LU2028103732.USD","LU1019634622.SGD","LU1934455277.USD","LU1242518931.SGD","SG9999014567.USD","SG9999004303.SGD","SG9999018857.SGD","LU2237443549.SGD","LU0203201768.USD","LU2097344357.USD","IE00B1XK9C88.USD","IE00BD6J9T35.USD","LU2237957811.SGD","IE00B3SWFQ91.USD","LU0390134368.USD","BK4579","LU0823414551.USD","LU2106854487.HKD","LU2468319806.SGD","LU2125909759.SGD","LU0528227936.USD","LU0476273544.USD","LU2250418816.HKD","LU2452424414.USD","LU2023251221.USD","LU2361045086.USD","LU0920840948.USD","IE000KEQY171.SGD","IE00BMPRXQ63.HKD","LU2360107168.USD","NVDS.UK","IE00BK4W5L77.USD","LU2091194634.USD","LU2168564222.USD","IE00B19Z8X17.USD","LU1923622614.USD","LU1935042991.SGD","SG9999014575.USD","LU1804176565.USD","LU0211328371.USD","LU0784384876.USD","IE00BJTD4N35.SGD","LU1051770623.HKD","IE0034235295.USD","LU0133085943.USD","LU0640478417.SGD","BK4503","LU2506951792.HKD","LU1691799644.USD","LU0109392836.USD","NVIW.SI","LU0210533765.USD","LU0203347892.USD","LU1868836591.USD","LU1496350502.SGD","LU1821325948.USD","LU1803068979.SGD","LU1323610961.USD","IE00B4JS1V06.HKD","LU0499090636.EUR","LU1852331112.SGD","IE00B1BXHZ80.USD","EFIV","LU2750360641.GBP","LU1951198990.SGD","IE0034235303.USD","LU2108987350.USD","HK0000819398.USD","LU0642271901.SGD","LU1003077747.HKD","IE00B4R5TH58.HKD","LU1778281490.HKD","LU0347712357.USD","LU1291159041.SGD","LU1861215975.USD","LU2125154778.USD","LU2491049909.HKD","LU2279689827.SGD","LU1481600234.SGD","LU0672654240.SGD","LU2931357623.SGD","LU1992135472.HKD","LU1989772840.SGD","LU0345777659.USD","LU0211327993.USD","IE00BJJMRX11.SGD","LU2087625088.SGD","BK4534","CHAT","IE00B775H168.HKD","TEK","BK4608","LU2381873111.SGD","LU1435385759.SGD","LU0553294199.USD","LU2112291526.USD","XLK","LU2125909247.SGD","LU0158827948.USD","LU1061106388.HKD","SG9999001176.SGD","LU2133065610.SGD","NVDU","LU1116320737.USD","SG9999014559.SGD","LU1983260115.SGD","LU0949170426.SGD","LU0820561818.USD","LU1712237335.SGD","SG9999002232.USD","LU0511384066.AUD","LU0784385170.HKD","LU0345769128.USD","LU0048584097.USD","LU0417517546.SGD","LU2552382058.USD","NVII","LU0820561909.HKD","BK4551","HK0000914686.HKD","LU0310800965.SGD","LU2471134523.USD","LU1629891620.HKD","LU0072462426.USD","LU0689626769.HKD","LU1037948541.HKD","LU0096362180.USD","LU2065171311.SGD","LU2286300806.USD","LU2552382215.SGD","LU3102509885.SGD","LU1242518857.USD","IE0034235188.USD","LU0210528500.USD","LU0965509101.SGD","LU0274383776.USD","LU2293690249.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650949927","title":"Astrazeneca's Wainua Fails Key Heart Disease Trial, Shares Tumble","url":"https://stock-news.laohu8.com/highlight/detail?id=2650949927","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650949927?lang=en_us&edition=fundamental","pubTime":"2026-07-09 14:38","pubTimestamp":1783579130,"startTime":"0","endTime":"0","summary":"UPDATE 5-AstraZeneca's Wainua fails key heart disease trial, shares tumbleWainua showed no effect in patients on stabilizer therapyFailure in heart-disease trial was unexpected by analystsDrug showed ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260709:nL6N43B0BS:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","LU2237443895.HKD","03165","LU2089984988.USD","IE00B19Z3B42.SGD","IONS","LU2089283258.USD","LU0225771236.USD","LU1267930227.SGD","LU0310800379.SGD","LU0889565916.HKD","IE0002270589.USD","BBIO","ALNY","LU1153585028.USD","PFE","SG9999013999.USD","LU0211326755.USD","LU1894683348.USD","LU1196032939.SGD","LU0211327993.USD","LU0114720955.EUR","LU2237443978.SGD","LU1267930573.SGD","BK4007","LU0827474353.SGD","LU0456855351.SGD","LU1894683264.USD","LU0960981461.USD","IE00B3T34201.USD","IE0009355771.USD","LU1481599808.USD","AZN.UK","LU0320765992.SGD","LU0203345920.USD","LU1291159041.SGD","LU0526926950.USD","OZEM","LU2433249047.HKD","LU2539964713.USD","LU1496350502.SGD","BK4592","LU0640478417.SGD","SG9999001176.USD","LU2125909247.SGD","LU0784384876.USD","LU1051770623.HKD","LU1323610961.USD","LU0058720904.USD","PBE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650946157","title":"Ionis Says Phase 3 Eplontersen Trial in Attr-cm Misses Primary Endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2650946157","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650946157?lang=en_us&edition=fundamental","pubTime":"2026-07-09 14:01","pubTimestamp":1783576876,"startTime":"0","endTime":"0","summary":"Ionis says Phase 3 eplontersen trial in ATTR-CM misses primary endpointIonis reported its Phase 3 CARDIO-TTRansform trial of eplontersen in ATTR-CM missed the primary endpoint versus placebo through W","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260709:nNDL6Ksx8r:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":10,"pageCount":7,"totalSize":200,"code":"91000000","status":"200"}]}}